PMID- 23073592
OWN - NLM
STAT- MEDLINE
DCOM- 20140227
LR  - 20171116
IS  - 1671-167X (Print)
IS  - 1671-167X (Linking)
VI  - 44
IP  - 5
DP  - 2012 Oct 18
TI  - [Retrospective assessment of anti-coagulative therapy and the incidence of acute 
      coronary syndrome during perioperative period in high-risk patients who had 
      suffered percutaneous coronary intervention recently].
PG  - 780-2
AB  - OBJECTIVE: To analyze the relationship between early anti-coagulative therapy and 
      acute coronary syndrome (ACS) in the high-risk patients who have suffered 
      percutaneous coronary intervention (PCI) recently during perioperative period of 
      non-cardiac surgery. METHODS: Patients who underwent scheduled non-cardiac 
      surgery in our hospital from May 2009 to May 2011 were reviewed, of whom, 135 
      patients had suffered PCI therapy within 1 year, insisting on the treatment by 
      taking aspirin and clopidogrel (plaix) orally. These patients were administrated 
      with heparin replacement treatment before scheduled surgeries. After surgeries, 
      patients were divided into non-anticoagulative therapy group (63 cases), low 
      molecular weight heparin (LMWH)-anticoagulative therapy group (36 cases) and 
      unfractionated heparin (UFH)-anticoagulative therapy group (38 cases). The 
      occurrence of ACS and hemorrhage in 3 days after operations was evaluated. 
      RESULTS: Of the 135 patients, 9 developed ACS in 3 days in non-anticoagulative 
      therapy group and none in other 2 groups (P<0.01). No statistical difference 
      among the 3 groups in quantity of the blood transfusion was found. CONCLUSION: 
      After scheduled non-cardiac surgeries, early and effective anticoagulative 
      therapy administrated in the high-risk patients who have suffered PCI recently 
      can obviously lower peri-operative incidence of acute coronary syndrome, and can 
      be incapable of increasing risk of post-operative hemorrhage.
FAU - Sun, Jian-ping
AU  - Sun JP
AD  - Department of Surgical Intensive Care Unit, Capital University of Medical 
      Sciences, Beijing, China. Cancer_sun@hotmail.com
FAU - Zhang, Jing-lan
AU  - Zhang JL
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Beijing Da Xue Xue Bao Yi Xue Ban
JT  - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health 
      sciences
JID - 101125284
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
SB  - IM
MH  - Acute Coronary Syndrome/*epidemiology/prevention & control
MH  - Aged
MH  - Aged, 80 and over
MH  - Anticoagulants/*therapeutic use
MH  - China/epidemiology
MH  - Cholecystectomy
MH  - Coronary Disease/*complications/therapy
MH  - Female
MH  - Gallbladder Diseases/complications/*surgery
MH  - Gastrectomy
MH  - Heparin, Low-Molecular-Weight/therapeutic use
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention
MH  - Perioperative Care
MH  - Perioperative Period
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Stomach Diseases/complications/*surgery
EDAT- 2012/10/18 06:00
MHDA- 2014/02/28 06:00
CRDT- 2012/10/18 06:00
PHST- 2012/10/18 06:00 [entrez]
PHST- 2012/10/18 06:00 [pubmed]
PHST- 2014/02/28 06:00 [medline]
PST - ppublish
SO  - Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Oct 18;44(5):780-2.