PMID- 23082252 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121022 LR - 20211021 IS - 2090-3006 (Electronic) IS - 2090-2999 (Print) IS - 2090-3006 (Linking) VI - 2012 DP - 2012 TI - Role of HLA in Hematopoietic Stem Cell Transplantation. PG - 680841 LID - 10.1155/2012/680841 [doi] LID - 680841 AB - The selection of hematopoietic stem cell transplantation (HSCT) donors includes a rigorous assessment of the availability and human leukocyte antigen (HLA) match status of donors. HLA plays a critical role in HSCT, but its involvement in HSCT is constantly in flux because of changing technologies and variations in clinical transplantation results. The increased availability of HSCT through the use of HLA-mismatched related and unrelated donors is feasible with a more complete understanding of permissible HLA mismatches and the role of killer-cell immunoglobulin-like receptor (KIR) genes in HSCT. The influence of nongenetic factors on the tolerability of HLA mismatching has recently become evident, demonstrating a need for the integration of both genetic and nongenetic variables in donor selection. FAU - Park, Meerim AU - Park M AD - Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea. FAU - Seo, Jong Jin AU - Seo JJ LA - eng PT - Journal Article DEP - 20121002 PL - Egypt TA - Bone Marrow Res JT - Bone marrow research JID - 101566202 PMC - PMC3467756 EDAT- 2012/10/20 06:00 MHDA- 2012/10/20 06:01 PMCR- 2012/10/02 CRDT- 2012/10/20 06:00 PHST- 2012/07/27 00:00 [received] PHST- 2012/09/03 00:00 [accepted] PHST- 2012/10/20 06:00 [entrez] PHST- 2012/10/20 06:00 [pubmed] PHST- 2012/10/20 06:01 [medline] PHST- 2012/10/02 00:00 [pmc-release] AID - 10.1155/2012/680841 [doi] PST - ppublish SO - Bone Marrow Res. 2012;2012:680841. doi: 10.1155/2012/680841. Epub 2012 Oct 2.