PMID- 23082962 OWN - NLM STAT- MEDLINE DCOM- 20140307 LR - 20220310 IS - 1755-5922 (Electronic) IS - 1755-5914 (Linking) VI - 31 IP - 4 DP - 2013 Aug TI - Updating the relationship between hyperhomocysteinemia lowering therapy and cardiovascular events. PG - e19-26 LID - 10.1111/1755-5922.12014 [doi] AB - Hyperhomocysteinemia (Hhcy) was defined as an independent risk factor for cardiovascular events. A number of clinical trials had investigated the relationship between Hhcy lowering treatment and cardiovascular diseases, however, the results of these studies remain controversial. This review article gave an over view of the homocysteine metabolisms and updated the recently published results in the role of Hhcy lowering therapy on cardiovascular events. CI - (c) 2012 John Wiley & Sons Ltd. FAU - Cheng, Xiaoshu AU - Cheng X AD - Department of Cardiology, Second Affiliated Hospital, Nanchang University, Nanchang, China. xiaoshu.cheng@gmail.com LA - eng PT - Journal Article PT - Review PL - England TA - Cardiovasc Ther JT - Cardiovascular therapeutics JID - 101319630 RN - 0 (Biomarkers) RN - 0LVT1QZ0BA (Homocysteine) SB - IM MH - Animals MH - Biomarkers/blood MH - Cardiovascular Diseases/blood/etiology/*prevention & control MH - Homocysteine/*blood MH - Humans MH - Hyperhomocysteinemia/blood/complications/diagnosis/*drug therapy MH - Risk Factors MH - Treatment Outcome OTO - NOTNLM OT - B vitamin OT - Cardiovascular disease OT - Folic acid OT - Homocysteine EDAT- 2012/10/23 06:00 MHDA- 2014/03/08 06:00 CRDT- 2012/10/23 06:00 PHST- 2012/10/23 06:00 [entrez] PHST- 2012/10/23 06:00 [pubmed] PHST- 2014/03/08 06:00 [medline] AID - 10.1111/1755-5922.12014 [doi] PST - ppublish SO - Cardiovasc Ther. 2013 Aug;31(4):e19-26. doi: 10.1111/1755-5922.12014.