PMID- 23085909 OWN - NLM STAT- MEDLINE DCOM- 20130301 LR - 20240326 IS - 1560-2281 (Electronic) IS - 1083-3668 (Print) IS - 1083-3668 (Linking) VI - 17 IP - 9 DP - 2012 Sep TI - Feasibility of in vivo intravascular photoacoustic imaging using integrated ultrasound and photoacoustic imaging catheter. PG - 96008-1 LID - 10.1117/1.JBO.17.9.096008 [doi] LID - 096008 AB - Pilot studies of in vivo combined intravascular ultrasound (IVUS) and intravascular photoacoustic (IVPA) imaging are reported. A recently introduced prototype of an integrated IVUS/IVPA imaging catheter consisting of a single-element ultrasound transducer and a light delivery system based on a single optical fiber was adapted and used for in vivo imaging of a coronary stent deployed in a rabbit's thoracic aorta in the presence of luminal blood. The results suggest that in vivo IVUS/IVPA imaging is feasible using the integrated IVUS/IVPA imaging catheter. The challenges of in vivo combined IVUS/IVPA imaging are discussed, and further improvements on the design of the catheter and the clinical imaging system are proposed. FAU - Karpiouk, Andrei B AU - Karpiouk AB AD - University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78712, USA. FAU - Wang, Bo AU - Wang B FAU - Amirian, James AU - Amirian J FAU - Smalling, Richard W AU - Smalling RW FAU - Emelianov, Stanislav Y AU - Emelianov SY LA - eng GR - R01 HL096981/HL/NHLBI NIH HHS/United States GR - HL 096981/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PL - United States TA - J Biomed Opt JT - Journal of biomedical optics JID - 9605853 SB - IM MH - Animals MH - Aorta, Thoracic/*diagnostic imaging MH - *Catheters, Indwelling MH - Computer-Aided Design MH - Elasticity Imaging Techniques/*instrumentation MH - Equipment Design MH - Equipment Failure Analysis MH - Feasibility Studies MH - Photoacoustic Techniques/*instrumentation MH - Rabbits MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Ultrasonography, Interventional/*instrumentation PMC - PMC3434470 EDAT- 2012/10/23 06:00 MHDA- 2013/03/02 06:00 PMCR- 2013/09/06 CRDT- 2012/10/23 06:00 PHST- 2012/10/23 06:00 [entrez] PHST- 2012/10/23 06:00 [pubmed] PHST- 2013/03/02 06:00 [medline] PHST- 2013/09/06 00:00 [pmc-release] AID - 1357028 [pii] AID - 11562SS [pii] AID - 10.1117/1.JBO.17.9.096008 [doi] PST - ppublish SO - J Biomed Opt. 2012 Sep;17(9):96008-1. doi: 10.1117/1.JBO.17.9.096008.