PMID- 23098827
OWN - NLM
STAT- MEDLINE
DCOM- 20130820
LR  - 20130311
IS  - 1618-131X (Electronic)
IS  - 1438-4639 (Linking)
VI  - 216
IP  - 3
DP  - 2013 Jun
TI  - Assessment of persistent organic pollutants levels in blood samples from Quintana 
      Roo, Mexico.
PG  - 284-9
LID - S1438-4639(12)00115-0 [pii]
LID - 10.1016/j.ijheh.2012.09.004 [doi]
AB  - The Stockholm Convention on persistent organic pollutants (POPs) sought to 
      determine baseline exposures to POPs in the general population; however, in 
      developing countries, exposure to these chemicals in hot spots may be an issue of 
      public health considering its magnitude. Therefore, the aim of this study was to 
      assess the levels of POPs in the blood of children living in three communities in 
      the Southeastern Region of Mexico. During 2007, we studied a total of 96 healthy 
      children (aged 6-12 years). Quantitative analyses were performed using gas 
      chromatography coupled with mass spectrometry. High levels of p,p'-DDT and its 
      principal metabolite, p,p'-DDE, were found in the blood of children living in the 
      three communities studied, the levels ranged from 463.5 to 9046.3 ng/g lipid and 
      from 490.8 to 57,712.4 ng/g lipid for DDT and DDE, respectively. In addition, 
      high levels of lindane (gamma-HCH) were found, with mean levels ranging between 575.4 
      and 6580.6 ng/g lipid. Moreover, children living in the study region were also 
      exposed to polychlorinated biphenyls (PCBs), and the levels of these compounds in 
      the blood of children were very similar between the communities with mean levels 
      of around 3000 ng/g lipid (total PCBs). In conclusion, we demonstrated that 
      children living in the studied communities were exposed to complex chemical 
      mixtures (DDT, DDE, lindane and PCBs) rather than to individual compounds. 
      Therefore, in future studies it is important to understand the potential 
      interactions between the components of these mixtures.
CI  - Copyright (c) 2012 Elsevier GmbH. All rights reserved.
FAU - Antonio, Trejo-Acevedo
AU  - Antonio TA
AD  - Departamento Toxicologia Ambiental, Facultad de Medicina, Universidad Autonoma de 
      San Luis Potosi, San Luis Potosi, Mexico.
FAU - Edith, Rivero-Perez Norma
AU  - Edith RP
FAU - Rogelio, Flores-Ramirez
AU  - Rogelio FR
FAU - Fernando, Diaz-Barriga
AU  - Fernando DB
FAU - Catalina, Ochoa Angeles
AU  - Catalina OA
FAU - Nelinho, Perez-Maldonado Ivan
AU  - Nelinho PM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121023
PL  - Germany
TA  - Int J Hyg Environ Health
JT  - International journal of hygiene and environmental health
JID - 100898843
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Insecticides)
SB  - IM
MH  - Child
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*blood
MH  - Insecticides/*blood
MH  - Male
MH  - Mexico
EDAT- 2012/10/27 06:00
MHDA- 2013/08/21 06:00
CRDT- 2012/10/27 06:00
PHST- 2012/01/27 00:00 [received]
PHST- 2012/08/29 00:00 [revised]
PHST- 2012/09/18 00:00 [accepted]
PHST- 2012/10/27 06:00 [entrez]
PHST- 2012/10/27 06:00 [pubmed]
PHST- 2013/08/21 06:00 [medline]
AID - S1438-4639(12)00115-0 [pii]
AID - 10.1016/j.ijheh.2012.09.004 [doi]
PST - ppublish
SO  - Int J Hyg Environ Health. 2013 Jun;216(3):284-9. doi: 
      10.1016/j.ijheh.2012.09.004. Epub 2012 Oct 23.