PMID- 23111939
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121101
LR  - 20141212
IS  - 1833-3516 (Print)
IS  - 1833-3516 (Linking)
VI  - 40
IP  - 4
DP  - 2010 Dec
TI  - Hyperbaric oxygen in the treatment of asphyxia in two newborn infants.
PG  - 218-20
AB  - Hypoxic-ischaemic encephalopathy (HIE) is a common cause of brain damage in the 
      neonatal period. Approximately 10% of births involve some degree of asphyxia, and 
      1% of these are severe. Current treatment has been limited to supportive measures 
      and the recent use of hypothermia. Beneficial effects of hyperbaric oxygen 
      treatment (HBOT) in neonatal asphyxia have been reported in the Chinese 
      literature. We report the use of HBOT to treat two term neonates with moderate 
      HIE according to Sarnat's classification. Clinical improvement occurred following 
      HBOT. A 50% decrease in the total creatine phosphokinase (CPK) level and a 40% 
      decrease in the CPK myocardial fraction were observed within 24 hours of the 
      first treatment. The decline in CPK levels may be related to a reduction in the 
      overall systemic inflammatory process and cannot be attributed solely to a 
      reduction in brain damage. HBOT may have a role in HIE.
FAU - Orozco-Gutierrez, Alberto
AU  - Orozco-Gutierrez A
AD  - Professor in the Department of Neonatology, Hospital Angeles del Pedregal, Camino 
      a Santa Teresa 1055-620, Heroes de Padierna, Magdalena Contreras, Distrito 
      Federal, Mexico, Phone: +52-(0)55-5568-4091, Fax: +52-(0)55-5652-8688, E-mail: 
      drorozco55@hotmail.com.
FAU - Rojas-Cerda, Lucilina
AU  - Rojas-Cerda L
FAU - Estrada, Rosa M
AU  - Estrada RM
FAU - Gil-Rosales, Cesar
AU  - Gil-Rosales C
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
EDAT- 2010/12/01 00:00
MHDA- 2010/12/01 00:01
CRDT- 2012/11/01 06:00
PHST- 2010/03/09 00:00 [received]
PHST- 2010/06/26 00:00 [accepted]
PHST- 2012/11/01 06:00 [entrez]
PHST- 2010/12/01 00:00 [pubmed]
PHST- 2010/12/01 00:01 [medline]
PST - ppublish
SO  - Diving Hyperb Med. 2010 Dec;40(4):218-20.