PMID- 23111972
OWN - NLM
STAT- MEDLINE
DCOM- 20130207
LR  - 20121031
IS  - 1128-3602 (Print)
IS  - 1128-3602 (Linking)
VI  - 16
IP  - 11
DP  - 2012 Oct
TI  - Mean platelet volume on admission is associated with further left ventricular 
      functions in primary PTCA patients.
PG  - 1567-9
AB  - AIM: In ST elevation myocardial infarction (STEMI) patients, mean platelet volume 
      (MPV) is associated with infarct related artery patency both before and after 
      reperfusion. In anterior STEMI patients successfully treated with primary 
      percutaneous coronary intervention (PCI), the relationship between left 
      ventricular (LV) function and MPV on admission is unknown. METHODS: 97 anterior 
      STEMI patients successfully revascularizated with PCI between January 2010 and 
      February 2011 are included. MPV on admission is recorded. All patients underwent 
      transthoracic echocardiography within 3 days or before discharge. Patients were 
      divided into two groups according to left ventricular ejection fraction (LVEF), 
      as systolic dysfunction (LVEF < 50%, 1st group) and normal systolic functions 
      (LVEF > 50%, 2nd group). The 1st group included 61 (47 males) patients and the 
      2nd group included 36 (35 males) patients. RESULTS: MPV was; 9.5+/-1.1 femtoliter 
      (fL) in the 1st and 8.8+/-0.8 fL in the second group. The difference between the 
      groups was significant (p = 0.001). There was a significant difference in the 
      Troponin I levels and white blood cell (WBC) counts on admission between two 
      groups (30+/-29 vs 12.2+/-15.1 ng/mL, p = 0.001 and 12.3+/-3.8 vs 10.6+/-3.4 
      counts x109/L, p = 0.027, respectively). CONCLUSIONS: In anterior STEMI patients 
      treated with percutaneous coronary intervention, increased MPV on admission is 
      associated with impairment in left ventricular systolic function.
FAU - Acar, Z
AU  - Acar Z
AD  - Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, 
      Trabzon, Turkey. drzeydin@gmail.co
FAU - Aga, M T
AU  - Aga MT
FAU - Kiris, A
AU  - Kiris A
FAU - Korkmaz, L
AU  - Korkmaz L
FAU - Erkan, H
AU  - Erkan H
FAU - Erkus, E
AU  - Erkus E
FAU - Akyz, A R
AU  - Akyz AR
FAU - Celik, S
AU  - Celik S
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
SB  - IM
MH  - Aged
MH  - Blood Platelets/*physiology
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/physiopathology/*surgery
MH  - *Percutaneous Coronary Intervention
MH  - Platelet Function Tests
MH  - Ventricular Dysfunction, Left/*physiopathology
MH  - Ventricular Function, Left/*physiology
EDAT- 2012/11/01 06:00
MHDA- 2013/02/08 06:00
CRDT- 2012/11/01 06:00
PHST- 2012/11/01 06:00 [entrez]
PHST- 2012/11/01 06:00 [pubmed]
PHST- 2013/02/08 06:00 [medline]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2012 Oct;16(11):1567-9.