PMID- 23115071
OWN - NLM
STAT- MEDLINE
DCOM- 20131205
LR  - 20171116
IS  - 2299-8306 (Electronic)
IS  - 0423-104X (Linking)
VI  - 63
IP  - 5
DP  - 2012
TI  - Incidence of metabolic syndrome and its risk factors among type 2 diabetes clinic 
      attenders in Isfahan, Iran.
PG  - 372-80
AB  - INTRODUCTION: At present, little data exists about the incidence of, and the risk 
      factors associated with, metabolic syndrome (MetS) in patients with type 2 
      diabetes mellitus (T2DM). The aims of this present study were to assess the 
      incidence and risk factors of MetS in people with T2DM using routinely collected 
      data from a clinical information system at Isfahan Endocrine and Metabolism 
      Research Centre, Iran. MATERIAL AND METHODS: During the mean (SD) follow-up 
      period of 11.7 (4.8) years, 3,047 patients with T2DM who were free of MetS at 
      baseline were examined to determine the incidence and predictors of progression 
      to MetS. The mean (SD) age of participants was 50.4 (11.0) years, with a mean 
      (SD) duration of diabetes of 6.3 (6.2) years at initial registration. A modified 
      National Cholesterol Education Programme- Adult Treatment Panel III definition 
      (with body mass index [BMI] instead of waist circumference) was used for the 
      MetS. RESULTS: The prevalence of MetS was 63.2% (95% CI: 62.3, 64.1). The 
      incidence of MetS was 28.5 (95% CI: 26.8, 30.2) (25.9 men and 30.9 women) per 
      1,000 patient-years based on 35,677 patient-years of follow-up. Multivariate 
      analysis revealed that higher body mass index (BMI) and education, lower HbA1c 
      and treatment with oral agent or insulin were associated with MetS. CONCLUSIONS: 
      These are the first estimates of the incidence and risk factors of MetS in 
      patients with T2DM in Iran. These findings show that the natural course of MetS 
      is dynamic. The clinical management of patients with T2DM will contribute 
      significantly to MetS prevention.
FAU - Janghorbani, Mohsen
AU  - Janghorbani M
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Isfahan 
      University of Medical Sciences, Isfahan, Iran. janghorbani@hlth.mui.ac.ir
FAU - Amini, Masoud
AU  - Amini M
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Endokrynol Pol
JT  - Endokrynologia Polska
JID - 0370674
RN  - 0 (Insulin)
SB  - IM
MH  - Adult
MH  - Body Composition
MH  - Body Mass Index
MH  - Diabetes Mellitus, Type 2/complications/*epidemiology
MH  - Disease Progression
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Insulin/*therapeutic use
MH  - Iran/epidemiology
MH  - Male
MH  - Metabolic Syndrome/*epidemiology/etiology
MH  - Middle Aged
MH  - Risk Factors
MH  - Waist Circumference
EDAT- 2012/11/02 06:00
MHDA- 2013/12/16 06:00
CRDT- 2012/11/02 06:00
PHST- 2012/11/02 06:00 [entrez]
PHST- 2012/11/02 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
PST - ppublish
SO  - Endokrynol Pol. 2012;63(5):372-80.