PMID- 2312346 OWN - NLM STAT- MEDLINE DCOM- 19900413 LR - 20190903 IS - 0018-2214 (Print) IS - 0018-2214 (Linking) VI - 22 IP - 1 DP - 1990 Jan TI - Expression of immunoreactivity for Ca-binding protein, spot 35 in the interstitial cell of the rat pineal organ. PG - 4-10 AB - In the rat pineal organ numerous stellate cells exhibited intense immunoreactivity for calcium-binding spot 35 protein. Because of their peculiar shape and ultrastructure, identical to those of intrapineal S-100-immunoreactive cells, the spot 35-immunoreactive stellate cells were identified as the interstitial cells. The comparison of the morphology and population density of spot 35-, S-100-, and GFAP (glial fibrillar acidic protein)-immunoreactive cells, suggests that spot 35-immunoreactive cells represent a major subpopulation of the interstitial cells, all of which are S-100-immunoreactive and generally considered to be of glial nature, while GFAP-immunoreactive cells represent a minor subpopulation of the interstitial cells located in the proximal part close to the pineal stalk. This is the first report describing the occurrence of the calcium-binding protein in cells of glial nature. FAU - Yamamoto, M AU - Yamamoto M AD - Department of Anatomy, School of Medicine, Kanazawa University, Japan. FAU - Kondo, H AU - Kondo H FAU - Yamakuni, T AU - Yamakuni T FAU - Takahashi, Y AU - Takahashi Y LA - eng PT - Journal Article PL - Netherlands TA - Histochem J JT - The Histochemical journal JID - 0163161 RN - 0 (Annexin A6) RN - 0 (Biomarkers) RN - 0 (Calcium-Binding Proteins) RN - 0 (S-100 calcium-binding protein alpha subunit) RN - 0 (S100 Proteins) SB - IM MH - Animals MH - Annexin A6 MH - *Biomarkers MH - Calcium-Binding Proteins/immunology/*metabolism MH - Immunohistochemistry MH - Male MH - Microscopy, Electron MH - Pineal Gland/immunology/*metabolism MH - Rats MH - Rats, Inbred Strains MH - S100 Proteins/immunology/metabolism EDAT- 1990/01/01 00:00 MHDA- 1990/01/01 00:01 CRDT- 1990/01/01 00:00 PHST- 1990/01/01 00:00 [pubmed] PHST- 1990/01/01 00:01 [medline] PHST- 1990/01/01 00:00 [entrez] AID - 10.1007/BF01962873 [doi] PST - ppublish SO - Histochem J. 1990 Jan;22(1):4-10. doi: 10.1007/BF01962873.