PMID- 23127660
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130620
LR  - 20121126
IS  - 1872-6283 (Electronic)
IS  - 0379-0738 (Linking)
VI  - 223
IP  - 1-3
DP  - 2012 Nov 30
TI  - Synthesis and impurity profiling of MDMA prepared from commonly available 
      starting materials.
PG  - 306-13
LID - S0379-0738(12)00460-4 [pii]
LID - 10.1016/j.forsciint.2012.10.006 [doi]
AB  - This work examines the synthesis of 3,4-methylenedioxy-N-methylamphetamine (MDMA) 
      from common starting materials that may be utilised by clandestine laboratory 
      operators. Piperonal was prepared from two common starting materials, piperine 
      (from pepper) and vanillin (a common flavouring). Piperine was converted to 
      piperonal by ozonolysis and oxidative cleavage with potassium permanganate and 
      tetrahydrofuran. Vanillin was converted to piperonal by demethylation with 
      pyridine and aluminium chloride followed by methylenation with dichloromethane. 
      The resulting piperonal samples were converted via a commonly encountered route 
      to MDMA. The impurities that indicate a particular route were identified and the 
      feasibility of each method was also assessed.
CI  - Copyright (c) 2012 Elsevier Ireland Ltd. All rights reserved.
FAU - Gallagher, Ryan
AU  - Gallagher R
AD  - Centre for Forensic Science, University of Technology Sydney, Sydney, NSW 2007, 
      Australia.
FAU - Shimmon, Ronald
AU  - Shimmon R
FAU - McDonagh, Andrew M
AU  - McDonagh AM
LA  - eng
PT  - Journal Article
DEP - 20121103
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
EDAT- 2012/11/07 06:00
MHDA- 2012/11/07 06:01
CRDT- 2012/11/07 06:00
PHST- 2012/03/19 00:00 [received]
PHST- 2012/10/03 00:00 [revised]
PHST- 2012/10/04 00:00 [accepted]
PHST- 2012/11/07 06:00 [entrez]
PHST- 2012/11/07 06:00 [pubmed]
PHST- 2012/11/07 06:01 [medline]
AID - S0379-0738(12)00460-4 [pii]
AID - 10.1016/j.forsciint.2012.10.006 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2012 Nov 30;223(1-3):306-13. doi: 
      10.1016/j.forsciint.2012.10.006. Epub 2012 Nov 3.