PMID- 23138412 OWN - NLM STAT- MEDLINE DCOM- 20130709 LR - 20220331 IS - 1651-2081 (Electronic) IS - 1650-1977 (Linking) VI - 45 IP - 3 DP - 2013 Mar TI - A three-week multidisciplinary in-patient rehabilitation programme had positive long-term effects in patients with ankylosing spondylitis: randomized controlled trial. PG - 260-7 LID - 10.2340/16501977-1078 [doi] AB - OBJECTIVE: To evaluate the mean overall effects over a 1-year period of a multidisciplinary in-patient rehabilitation programme for patients with ankylosing spondylitis. DESIGN: Observer-blinded, randomized controlled trial, with assessments made after 4 and 12 months. PATIENTS: Forty-six patients received a 3-week in-patient rehabilitation programme and 49 patients received treatment as usual. METHODS: Primary outcomes were disease activity measured with the Bath Ankylosing Spondylitis Disease Activity Scale (BASDAI), and function measured with the Bath Ankylosing Spondylitis Functional Index (BASFI). Secondary outcomes included well-being, spinal and hip mobility, and health-related quality of life measured with the Medical Outcome Study Short Form-36. Overall treatment effects were estimated with Mixed models repeated measures analyses. RESULTS: Significant overall treatment effects in favour of the rehabilitation group were found in the BASDAI score (mean difference over the 1-year period -10.0, 95% confidence interval: -3.7 to -16.3), in well-being (-7.3, 95% confidence interval: -1.0 to -14.7), and in the Medical Outcome Study Short Form-36 variables social functioning, role physical, role mental and bodily pain (mean differences ranging from 5.8 (pain) to 10.7 (role physical)). CONCLUSION: A 3-week in-patient rehabilitation programme had positive overall effects on disease activity, pain, function and well-being, and should be considered an important complement to medical disease management in persons with ankylosing spondylitis. FAU - Kjeken, Ingvild AU - Kjeken I AD - National Resource Center for Rehabilitation in Rheumatology, Diakonhjemmets Hospital, Oslo, Norway. ingvild.kjeken@diakonsyk.no FAU - Bo, Ingvild AU - Bo I FAU - Ronningen, Aud AU - Ronningen A FAU - Spada, Cristina AU - Spada C FAU - Mowinckel, Petter AU - Mowinckel P FAU - Hagen, Kare Birger AU - Hagen KB FAU - Dagfinrud, Hanne AU - Dagfinrud H LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - Sweden TA - J Rehabil Med JT - Journal of rehabilitation medicine JID - 101088169 SB - IM MH - Adult MH - *Disability Evaluation MH - Female MH - Health Status Indicators MH - Hospitalization MH - Humans MH - Male MH - Middle Aged MH - Patient Care Team MH - Physical Therapy Modalities MH - Quality of Life MH - Recovery of Function MH - Spondylitis, Ankylosing/*rehabilitation EDAT- 2012/11/10 06:00 MHDA- 2013/07/10 06:00 CRDT- 2012/11/10 06:00 PHST- 2012/11/10 06:00 [entrez] PHST- 2012/11/10 06:00 [pubmed] PHST- 2013/07/10 06:00 [medline] AID - 10.2340/16501977-1078 [doi] PST - ppublish SO - J Rehabil Med. 2013 Mar;45(3):260-7. doi: 10.2340/16501977-1078.