PMID- 23149183
OWN - NLM
STAT- MEDLINE
DCOM- 20130501
LR  - 20131121
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 90
IP  - 5
DP  - 2013 Feb
TI  - High prevalence of infections and pathological changes in burbot (Lota lota) from 
      a polluted lake (Lake Mjosa, Norway).
PG  - 1711-8
LID - S0045-6535(12)01256-8 [pii]
LID - 10.1016/j.chemosphere.2012.10.017 [doi]
AB  - The aim of the present study was to investigate whether exposure to high levels 
      of persistent organic pollutants (POPs) affected a fish population in Lake Mjosa. 
      Lake Mjosa is known to be contaminated by polybrominated diphenyl ethers (PBDEs), 
      a subgroup of brominated flame retardants from local industrial activities. Fish 
      from Lake Losna, a less contaminated lake located close to Lake Mjosa, was used 
      as reference (control). The sampling of burbot (Lota lota) was carried out 
      between 2005 and 2008. Hepatic levels of POPs were analysed in burbot from the 
      two lakes, and the fish were examined for bacterial- and parasite infection and 
      histopathological changes. The levels of polychlorinated biphenyls (PCBs), 
      dichlorodiphenyltrichloroethanes (DDTs), and PBDEs were about 10, 15 and 300 
      times higher in fish from Lake Mjosa compared to fish from Lake Losna. 
      Mycobacterium salmoniphilum was present in 7% and 35% of the fish from Lake Losna 
      and Lake Mjosa respectively. Significantly higher number of external and visceral 
      macroscopic lesions, histopathological diffuse changes and granulomas were seen 
      in fish from Lake Mjosa compared to Lake Losna. Furthermore the parasite 
      infection was higher and the hepatic lipid content was significantly lower in 
      burbot from Lake Mjosa. The results of the present study suggest that the high 
      level of contamination in Lake Mjosa could have a negative impact on the health 
      status of wild fish inhabiting the lake.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Berg, Vidar
AU  - Berg V
AD  - Norwegian School of Veterinary Science, Oslo, Norway. vidar.berg@nvh.no
FAU - Zerihun, Mulualem A
AU  - Zerihun MA
FAU - Jorgensen, Anders
AU  - Jorgensen A
FAU - Lie, Elisabeth
AU  - Lie E
FAU - Dale, Ole B
AU  - Dale OB
FAU - Skaare, Janneche Utne
AU  - Skaare JU
FAU - Lyche, Jan L
AU  - Lyche JL
LA  - eng
PT  - Journal Article
DEP - 20121111
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Flame Retardants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Water Pollutants, Chemical)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - Environmental Monitoring
MH  - Fish Diseases/*epidemiology/microbiology/pathology
MH  - Flame Retardants/analysis/metabolism/toxicity
MH  - Gadiformes/metabolism/*microbiology
MH  - Halogenated Diphenyl Ethers/analysis/metabolism/toxicity
MH  - Lakes/chemistry
MH  - Liver/metabolism
MH  - Norway
MH  - Polychlorinated Biphenyls/analysis/metabolism/toxicity
MH  - Prevalence
MH  - Water Pollutants, Chemical/*analysis/metabolism/toxicity
MH  - Water Pollution, Chemical/statistics & numerical data
EDAT- 2012/11/15 06:00
MHDA- 2013/05/02 06:00
CRDT- 2012/11/15 06:00
PHST- 2012/04/17 00:00 [received]
PHST- 2012/08/24 00:00 [revised]
PHST- 2012/10/17 00:00 [accepted]
PHST- 2012/11/15 06:00 [entrez]
PHST- 2012/11/15 06:00 [pubmed]
PHST- 2013/05/02 06:00 [medline]
AID - S0045-6535(12)01256-8 [pii]
AID - 10.1016/j.chemosphere.2012.10.017 [doi]
PST - ppublish
SO  - Chemosphere. 2013 Feb;90(5):1711-8. doi: 10.1016/j.chemosphere.2012.10.017. Epub 
      2012 Nov 11.