PMID- 23153459
OWN - NLM
STAT- MEDLINE
DCOM- 20130820
LR  - 20131121
IS  - 1873-1899 (Electronic)
IS  - 0734-9750 (Linking)
VI  - 31
IP  - 2
DP  - 2013 Mar-Apr
TI  - Coupling microbial catabolic actions with abiotic redox processes: a new recipe 
      for persistent organic pollutant (POP) removal.
PG  - 246-56
LID - S0734-9750(12)00187-5 [pii]
LID - 10.1016/j.biotechadv.2012.11.002 [doi]
AB  - The continuous release of toxic persistent organic pollutants (POPs) into the 
      environment has raised a need for effective cleanup methods. The tremendous 
      natural diversity of microbial catabolic mechanisms suggests that catabolic 
      routes may be applied to the remediation of POP-contaminated fields. A large 
      number of the recalcitrant xenobiotics have been shown to be removable via the 
      natural catabolic mechanisms of microbes, and detailed biochemical studies of the 
      catabolic methods, together with the development of sophisticated genetic 
      engineering, have led to the use of synthetic microbes for the bioremediation of 
      POPs. However, the steric effects of substituted halogen moieties, microbe 
      toxicity, and the low bioavailability of POPs still deteriorate the efficiency of 
      removal strategies based on natural and synthetic catabolic mechanisms. Recently, 
      abiotic redox processes that induce rapid reductive dehalogenation, hydroxyl 
      radical-based oxidation, or electron shuttling have been reasonably coupled with 
      microbial catabolic actions, thereby compensating for the drawbacks of biotic 
      processes in POP removal. In this review, we first compare the pros and cons of 
      individual methodologies (i.e., the natural and synthetic catabolism of microbes 
      and the abiotic processes involving zero-valent irons, advanced oxidation 
      processes, and small organic stimulants) for POP removal. We then highlight 
      recent trends in coupling the biotic-abiotic methodologies and discuss how the 
      processes are both feasible and superior to individual methodologies for POP 
      cleanup. Cost-effective and environmentally sustainable abiotic redox actions 
      could enhance the microbial bioremediation potential for POPs.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Jeon, Jong-Rok
AU  - Jeon JR
AD  - Corporate R&D, LG Chem Research Park, Daejeon 305-380, Republic of Korea.
FAU - Murugesan, Kumarasamy
AU  - Murugesan K
FAU - Nam, In-Hyun
AU  - Nam IH
FAU - Chang, Yoon-Seok
AU  - Chang YS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20121112
PL  - England
TA  - Biotechnol Adv
JT  - Biotechnology advances
JID - 8403708
RN  - 0 (Environmental Pollutants)
RN  - 0 (Organic Chemicals)
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - *Biodegradation, Environmental
MH  - Biotechnology/*methods
MH  - Cost-Benefit Analysis
MH  - Environmental Pollutants/chemistry/*metabolism
MH  - Industrial Microbiology/*methods
MH  - Iron/metabolism
MH  - Organic Chemicals/chemistry/*metabolism
MH  - Oxidation-Reduction
EDAT- 2012/11/17 06:00
MHDA- 2013/08/21 06:00
CRDT- 2012/11/17 06:00
PHST- 2012/06/15 00:00 [received]
PHST- 2012/10/01 00:00 [revised]
PHST- 2012/11/03 00:00 [accepted]
PHST- 2012/11/17 06:00 [entrez]
PHST- 2012/11/17 06:00 [pubmed]
PHST- 2013/08/21 06:00 [medline]
AID - S0734-9750(12)00187-5 [pii]
AID - 10.1016/j.biotechadv.2012.11.002 [doi]
PST - ppublish
SO  - Biotechnol Adv. 2013 Mar-Apr;31(2):246-56. doi: 10.1016/j.biotechadv.2012.11.002. 
      Epub 2012 Nov 12.