PMID- 23158037 OWN - NLM STAT- MEDLINE DCOM- 20131125 LR - 20220318 IS - 1728-7731 (Electronic) IS - 1726-4901 (Linking) VI - 75 IP - 11 DP - 2012 Nov TI - Sonographic presentations of metaplastic breast cancers. PG - 589-94 LID - S1726-4901(12)00208-0 [pii] LID - 10.1016/j.jcma.2012.08.005 [doi] AB - BACKGROUND: Metaplastic carcinoma of the breast (MPCB) is a rare breast cancer. We reviewed sonographic findings for MPCB. METHODS: Grayscale ultrasonography (US), color Doppler US (CDUS), and spectral Doppler US (SDUS) findings for 10 patients with MPCB breast were retrospectively reviewed. RESULTS: The prevalence of MPCB was 3.9% among cases of breast cancer in our hospital. All patients had a rapidly growing palpable breast mass. The mean lesion size was 5.7 cm. On US, the lesion shape was most commonly gently lobulated (90%); only one showed an irregular shape (10%). The lesion shape was most commonly circumscribed (90%). Nine tumors had an abrupt boundary and one had an indistinct boundary. Lesion echogenicity was hypoechoic and very hypoechoic (40%), hypoechoic (30%), or very hypoechoic, hypoechoic, and hyperechoic (30%). All our cases had cystic parts with posterior acoustic enhancement, representing necrosis or hemorrhage. CDUS showed peripheral, central and marginal color flow signals. The resistivity index (RI) of tumor vessels in the lesions ranged from 0.7 to 1.3. The axillary lymph nodes were enlarged on US and were positive for metastasis in three cases (30%). CONCLUSION: MPCB is a rare rapidly growing tumor. US findings included gently lobulated, complex mass lesion with cystic parts and posterior acoustic enhancement, representing necrosis or hemorrhage. Increased color flow signals and relative high RI of the feeding arteries were also seen. CI - Copyright (c) 2012. Published by Elsevier B.V. FAU - Lai, Yi-Chen AU - Lai YC AD - Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. FAU - Hsu, Chih-Yi AU - Hsu CY FAU - Chou, Yi-Hong AU - Chou YH FAU - Tiu, Chui-Mei AU - Tiu CM FAU - Tseng, Ling-Ming AU - Tseng LM FAU - Wang, Hsin-Kai AU - Wang HK FAU - Chiou, Hong-Jen AU - Chiou HJ LA - eng PT - Journal Article DEP - 20121009 PL - Netherlands TA - J Chin Med Assoc JT - Journal of the Chinese Medical Association : JCMA JID - 101174817 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Breast Neoplasms/*diagnostic imaging/pathology MH - Female MH - Humans MH - Middle Aged MH - Neoplasm Metastasis MH - Ultrasonography EDAT- 2012/11/20 06:00 MHDA- 2013/12/16 06:00 CRDT- 2012/11/20 06:00 PHST- 2011/12/30 00:00 [received] PHST- 2012/03/30 00:00 [accepted] PHST- 2012/11/20 06:00 [entrez] PHST- 2012/11/20 06:00 [pubmed] PHST- 2013/12/16 06:00 [medline] AID - S1726-4901(12)00208-0 [pii] AID - 10.1016/j.jcma.2012.08.005 [doi] PST - ppublish SO - J Chin Med Assoc. 2012 Nov;75(11):589-94. doi: 10.1016/j.jcma.2012.08.005. Epub 2012 Oct 9.