PMID- 23162006 OWN - NLM STAT- MEDLINE DCOM- 20130418 LR - 20220409 IS - 1940-1574 (Electronic) IS - 0003-3197 (Linking) VI - 64 IP - 3 DP - 2013 Apr TI - An analysis of the relationship between ankle-brachial index and estimated glomerular filtration rate in type 2 diabetes. PG - 237-41 LID - 10.1177/0003319712464515 [doi] AB - We investigated the relationship between peripheral arterial disease (PAD) and renal function in patients with type 2 diabetes mellitus (T2DM). We enrolled 2057 hospitalized patients with T2DM and measured kidney function and ankle-brachial index (ABI). The estimated glomerular filtration rate (eGFR) was derived using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and ABI was grouped as low (<0.9), low-normal (0.9-1.09), normal (1.1-1.3), and high (>1.3). Logistic regression was used to evaluate the associations of eGFR with ABI. Generally speaking, the ABI was negatively correlated with systolic blood pressure, fasting C-peptide, total cholesterol, and low-density lipoprotein cholesterol while positively correlated with body mass index (P < .05 to <.01). Only a low ABI was positively correlated with eGFR (P < .01). In addition to the association of the ABI with cardiovascular events, stroke, and PAD, ABI may also predict the change in renal function in patients with T2DM. FAU - Jin, Xing AU - Jin X AD - Department of Endocrinology, Nanjing Medical University Affiliated Nanjing Hospital, Nanjing, China. FAU - Ma, Jian-hua AU - Ma JH FAU - Shen, Yun AU - Shen Y FAU - Luo, Yong AU - Luo Y FAU - Su, Xiao-fei AU - Su XF FAU - Chen, Ying-yue AU - Chen YY FAU - Qi, Shao-kang AU - Qi SK FAU - Wu, Jin-dan AU - Wu JD LA - eng PT - Journal Article DEP - 20121115 PL - United States TA - Angiology JT - Angiology JID - 0203706 SB - IM CIN - Angiology. 2013 Apr;64(3):243. PMID: 23299170 CIN - Angiology. 2013 Apr;64(3):242. PMID: 23460454 MH - Adult MH - Aged MH - Aged, 80 and over MH - *Ankle Brachial Index MH - Body Mass Index MH - Diabetes Mellitus, Type 2/*epidemiology/*physiopathology MH - Diabetic Angiopathies/*physiopathology MH - Female MH - Glomerular Filtration Rate/*physiology MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Peripheral Arterial Disease/*physiopathology MH - Renal Insufficiency, Chronic EDAT- 2012/11/20 06:00 MHDA- 2013/04/20 06:00 CRDT- 2012/11/20 06:00 PHST- 2012/11/20 06:00 [entrez] PHST- 2012/11/20 06:00 [pubmed] PHST- 2013/04/20 06:00 [medline] AID - 0003319712464515 [pii] AID - 10.1177/0003319712464515 [doi] PST - ppublish SO - Angiology. 2013 Apr;64(3):237-41. doi: 10.1177/0003319712464515. Epub 2012 Nov 15.