PMID- 23163497 OWN - NLM STAT- MEDLINE DCOM- 20131112 LR - 20181202 IS - 1742-1241 (Electronic) IS - 1368-5031 (Linking) VI - 66 IP - 12 DP - 2012 Dec TI - Adverse effects of homeopathy: a systematic review of published case reports and case series. PG - 1178-88 LID - 10.1111/ijcp.12026 [doi] AB - AIM: The aim of this systematic review was to critically evaluate the evidence regarding the adverse effects (AEs) of homeopathy. METHOD: Five electronic databases were searched to identify all relevant case reports and case series. RESULTS: In total, 38 primary reports met our inclusion criteria. Of those, 30 pertained to direct AEs of homeopathic remedies; and eight were related to AEs caused by the substitution of conventional medicine with homeopathy. The total number of patients who experienced AEs of homeopathy amounted to 1159. Overall, AEs ranged from mild-to-severe and included four fatalities. The most common AEs were allergic reactions and intoxications. Rhus toxidendron was the most frequently implicated homeopathic remedy. CONCLUSION: Homeopathy has the potential to harm patients and consumers in both direct and indirect ways. Clinicians should be aware of its risks and advise their patients accordingly. CI - (c) 2012 Blackwell Publishing Ltd. FAU - Posadzki, P AU - Posadzki P AD - Complementary Medicine, Peninsula Medical School, Exeter, UK. paul.posadzki@pcmd.ac.uk FAU - Alotaibi, A AU - Alotaibi A FAU - Ernst, E AU - Ernst E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PT - Systematic Review PL - India TA - Int J Clin Pract JT - International journal of clinical practice JID - 9712381 RN - 0 (Materia Medica) SB - IM CIN - Int J Clin Pract. 2013 Apr;67(4):385-6. PMID: 23521332 CIN - Int J Clin Pract. 2013 Apr;67(4):386-7. PMID: 23521333 CIN - Int J Clin Pract. 2013 Apr;67(4):388-9. PMID: 23521335 CIN - Int J Clin Pract. 2013 Apr;67(4):389. PMID: 23521336 CIN - Int J Clin Pract. 2013 Sep;67(9):923-6. PMID: 23952470 CIN - J Altern Complement Med. 2014 Jan;20(1):67-8. PMID: 24325261 MH - Drug Eruptions/etiology MH - Epidemiologic Methods MH - Humans MH - Materia Medica/*adverse effects/poisoning EDAT- 2012/11/21 06:00 MHDA- 2013/11/13 06:00 CRDT- 2012/11/21 06:00 PHST- 2012/11/21 06:00 [entrez] PHST- 2012/11/21 06:00 [pubmed] PHST- 2013/11/13 06:00 [medline] AID - 10.1111/ijcp.12026 [doi] PST - ppublish SO - Int J Clin Pract. 2012 Dec;66(12):1178-88. doi: 10.1111/ijcp.12026.