PMID- 23170095
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121122
LR  - 20211021
IS  - 1738-5555 (Electronic)
IS  - 1738-5520 (Print)
IS  - 1738-5520 (Linking)
VI  - 42
IP  - 10
DP  - 2012 Oct
TI  - Absence and Resolution of Fragmented QRS Predict Reversible Myocardial Ischemia 
      With Higher Probability of ST Segment Resolution in Patients With ST Segment 
      Elevation Myocardial Infarction.
PG  - 674-83
LID - 10.4070/kcj.2012.42.10.674 [doi]
AB  - BACKGROUND AND OBJECTIVES: Fragmented QRS complexes (fQRS) are associated with 
      increased morbidity and mortality. The causative relationship between fQRS and 
      cardiac fibrosis has been shown, but whether the presence and the number of fQRS 
      on admission of electrocardiogram (ECG) predicts ST segment resolution in 
      patients undergoing primary percutaneous coronary intervention (p-PCI) has not 
      been investigated until now. SUBJECTS AND METHODS: This study included one 
      hundred and eighty-four consecutive patients with ST elevation myocardial 
      infarction (STEMI) who underwent p-PCI. The presence or absence of fQRS on pre 
      and post-PCI ECG and their relation with myocardial infarction and reperfusion 
      parameters were investigated. RESULTS: Patients with fQRS on admission of ECG or 
      newly developed fQRS after p-PCI had increased inflammatory markers, higher 
      cardiac enzyme levels, increased pain to balloon time, prolonged QRS time, more 
      extended coronary involvement and more frequent Q waves on ECG in comparison to 
      patients with absence or resolved fQRS. The presence and higher number of fQRS on 
      admission or post-PCI ECGs were significantly related with low percent of ST 
      resolution and myocardial reperfusion parameters. The area under the receiver 
      operating characteristics curve values for the presence and number of fQRS to 
      detect Thrombolysis in Myocardial Infarction Blush Grade 0 and 1, were 0.682 and 
      0.703. CONCLUSION: In our study, fQRS was significantly related to infarction and 
      myocardial reperfusion parameters before and after p-PCI. Successful myocardial 
      reperfusion by p-PCI caused the reduction in number of fQRS and QRS time with 
      higher ST resolution. fQRS may be useful in identifying the patients at higher 
      cardiac risk with increased ischemic jeopardized or infarcted myocardium, and 
      persistent or newly developed fQRS may predict low percent of ST segment 
      resolution in patients undergoing p-PCI.
FAU - Cetin, Mustafa
AU  - Cetin M
AD  - Department of Cardiology, Rize Education and Research Hospital, Rize, Turkey.
FAU - Kocaman, Sinan Altan
AU  - Kocaman SA
FAU - Kiris, Tuncay
AU  - Kiris T
FAU - Erdogan, Turan
AU  - Erdogan T
FAU - Canga, Aytun
AU  - Canga A
FAU - Durakoglugil, Murtaza Emre
AU  - Durakoglugil ME
FAU - Cicek, Yuksel
AU  - Cicek Y
FAU - Dogan, Sitki
AU  - Dogan S
FAU - Satiroglu, Omer
AU  - Satiroglu O
LA  - eng
PT  - Journal Article
DEP - 20121031
PL  - Korea (South)
TA  - Korean Circ J
JT  - Korean circulation journal
JID - 101247141
PMC - PMC3493804
OTO - NOTNLM
OT  - Electrocardiography
OT  - Fragmented QRS
OT  - Marker
OT  - Myocardial infarction
OT  - Reperfusion
COIS- The authors have no financial conflicts of interest.
EDAT- 2012/11/22 06:00
MHDA- 2012/11/22 06:01
PMCR- 2012/10/01
CRDT- 2012/11/22 06:00
PHST- 2012/02/02 00:00 [received]
PHST- 2012/04/24 00:00 [revised]
PHST- 2012/05/15 00:00 [accepted]
PHST- 2012/11/22 06:00 [entrez]
PHST- 2012/11/22 06:00 [pubmed]
PHST- 2012/11/22 06:01 [medline]
PHST- 2012/10/01 00:00 [pmc-release]
AID - 10.4070/kcj.2012.42.10.674 [doi]
PST - ppublish
SO  - Korean Circ J. 2012 Oct;42(10):674-83. doi: 10.4070/kcj.2012.42.10.674. Epub 2012 
      Oct 31.