PMID- 23171833
OWN - NLM
STAT- MEDLINE
DCOM- 20131022
LR  - 20211021
IS  - 1469-8978 (Electronic)
IS  - 0033-2917 (Linking)
VI  - 43
IP  - 5
DP  - 2013 May
TI  - A 4-year prospective observational follow-up study of course and predictors of 
      course in body dysmorphic disorder.
PG  - 1109-17
LID - 10.1017/S0033291712001730 [doi]
AB  - BACKGROUND: This report prospectively examines the 4-year course, and predictors 
      of course, of body dysmorphic disorder (BDD), a common and often severe disorder. 
      No prior studies have prospectively examined the course of BDD in individuals 
      ascertained for BDD. Method The Longitudinal Interval Follow-Up Evaluation (LIFE) 
      assessed weekly BDD symptoms and treatment received over 4 years for 166 broadly 
      ascertained adults and adolescents with current BDD at intake. Kaplan-Meier life 
      tables were constructed for time to remission and relapse. Full remission was 
      defined as minimal or no BDD symptoms, and partial remission as less than full 
      DSM-IV criteria, for at least 8 consecutive weeks. Full relapse and partial 
      relapse were defined as meeting full BDD criteria for at least 2 consecutive 
      weeks after attaining full or partial remission respectively. Cox proportional 
      hazards regression examined predictors of remission and relapse. RESULTS: Over 4 
      years, the cumulative probability was 0.20 for full remission and 0.55 for full 
      or partial remission from BDD. A lower likelihood of full or partial remission 
      was predicted by more severe BDD symptoms at intake, longer lifetime duration of 
      BDD, and being an adult. Among partially or fully remitted subjects, the 
      cumulative probability was 0.42 for subsequent full relapse and 0.63 for 
      subsequent full or partial relapse. More severe BDD at intake and earlier age at 
      BDD onset predicted full or partial relapse. Eighty-eight percent of subjects 
      received mental health treatment during the follow-up period. CONCLUSIONS: In 
      this observational study, BDD tended to be chronic. Several intake variables 
      predicted greater chronicity of BDD.
FAU - Phillips, K A
AU  - Phillips KA
AD  - Rhode Island Hospital, Providence, RI 02903, USA. Katharine_Phillips@brown.edu
FAU - Menard, W
AU  - Menard W
FAU - Quinn, E
AU  - Quinn E
FAU - Didie, E R
AU  - Didie ER
FAU - Stout, R L
AU  - Stout RL
LA  - eng
GR  - R01 MH060241/MH/NIMH NIH HHS/United States
GR  - K24-MH063975/MH/NIMH NIH HHS/United States
GR  - R01-MH60241/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20120829
PL  - England
TA  - Psychol Med
JT  - Psychological medicine
JID - 1254142
RN  - 0 (Psychotropic Drugs)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Body Dysmorphic Disorders/*psychology/therapy
MH  - Chronic Disease
MH  - Delusions/psychology
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - *Disease Progression
MH  - Epidemiologic Methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Outcome Assessment, Health Care/*statistics & numerical data
MH  - Psychotherapy/statistics & numerical data
MH  - Psychotropic Drugs/therapeutic use
MH  - Recurrence
MH  - Remission Induction
EDAT- 2012/11/23 06:00
MHDA- 2013/10/23 06:00
CRDT- 2012/11/23 06:00
PHST- 2012/11/23 06:00 [entrez]
PHST- 2012/11/23 06:00 [pubmed]
PHST- 2013/10/23 06:00 [medline]
AID - S0033291712001730 [pii]
AID - 10.1017/S0033291712001730 [doi]
PST - ppublish
SO  - Psychol Med. 2013 May;43(5):1109-17. doi: 10.1017/S0033291712001730. Epub 2012 
      Aug 29.