PMID- 2317272 OWN - NLM STAT- MEDLINE DCOM- 19900504 LR - 20190907 IS - 0735-7044 (Print) IS - 0735-7044 (Linking) VI - 104 IP - 1 DP - 1990 Feb TI - Reflex facilitation of the rabbit nictitating membrane response by an auditory stimulus as a function of interstimulus interval. PG - 11-20 AB - The ability of an auditory stimulus to facilitate the amplitude and latency of the unconditioned nictitating membrane (NM) response in rabbits was investigated over a wide range of interstimulus intervals (ISIs) for both delay (Experiments 1-4) and trace (Experiments 3 and 4) procedures. The auditory stimulus was a 1000-Hz tone (T) at either 85 or 95 dB, and the reflex-eliciting stimulus was a 2.0 psi (pounds per square inch) corneal air puff (AP). The results indicate that (a) robust facilitation of the NM response, as measured by an increased amplitude and a reduced latency, can be obtained at long ISIs (2,000-32,000 ms); (b) increasing the tone intensity can increase reflex facilitation of the peak amplitude; (c) at comparable ISIs, delay procedures produce more facilitation of both amplitude and latency than do trace procedures; and (d) when trace procedures are used, amplitude and latency facilitation by a 125-ms tone follows an inverted U-shaped ISI function in which facilitation peaks between 125 and 500 ms, rapidly decreases between 1,000 and 2,000 ms, and disappears by 4,000 ms. FAU - Weisz, D J AU - Weisz DJ AD - Yale University. FAU - Walts, C AU - Walts C LA - eng GR - 5R01 MH39450/MH/NIMH NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Behav Neurosci JT - Behavioral neuroscience JID - 8302411 SB - IM MH - Animals MH - *Arousal MH - *Association Learning MH - Attention MH - *Blinking MH - *Conditioning, Classical MH - *Learning MH - Loudness Perception MH - *Memory MH - *Mental Recall MH - *Pitch Perception MH - Rabbits MH - Reaction Time EDAT- 1990/02/01 00:00 MHDA- 1990/02/01 00:01 CRDT- 1990/02/01 00:00 PHST- 1990/02/01 00:00 [pubmed] PHST- 1990/02/01 00:01 [medline] PHST- 1990/02/01 00:00 [entrez] AID - 10.1037//0735-7044.104.1.11 [doi] PST - ppublish SO - Behav Neurosci. 1990 Feb;104(1):11-20. doi: 10.1037//0735-7044.104.1.11.