PMID- 23174394
OWN - NLM
STAT- MEDLINE
DCOM- 20130317
LR  - 20211021
IS  - 2045-7960 (Print)
IS  - 2045-7979 (Electronic)
IS  - 2045-7960 (Linking)
VI  - 21
IP  - 4
DP  - 2012 Dec
TI  - The role of cognitive functioning in the outcome of those at clinical high risk 
      for developing psychosis.
PG  - 335-42
LID - 10.1017/S204579601200042X [doi]
AB  - Although it is well established that cognitive impairment is a common feature of 
      schizophrenia, only recently has cognitive functioning been prospectively studied 
      in individuals at clinical high risk (CHR) for developing psychosis. To date, 
      both cross-sectional and longitudinal studies have been conducted in the CHR 
      population and in the context of later conversion to psychosis. A comprehensive 
      review of the literature suggests that CHR individuals have general and specific 
      baseline cognitive deficits compared to healthy controls. As a group, their 
      cognitive course, tends to remain stable over time and in this way does not 
      differ from healthy controls. For those who go on to develop a full-blown 
      psychotic illness compared to those who do not convert, there appeared to be 
      minimal differences at baseline with respect to cognition, although over time the 
      converters may show deterioration in certain cognitive abilities compared to the 
      non-converters. However, for many cognitive domains results are mixed, and may 
      result from methodological limitations.
FAU - Addington, J
AU  - Addington J
FAU - Barbato, M
AU  - Barbato M
LA  - eng
PT  - Editorial
PT  - Review
PL  - England
TA  - Epidemiol Psychiatr Sci
JT  - Epidemiology and psychiatric sciences
JID - 101561091
SB  - IM
MH  - Cognition
MH  - Cognition Disorders/*epidemiology/etiology
MH  - Humans
MH  - Neuropsychological Tests
MH  - Prodromal Symptoms
MH  - Psychotic Disorders/complications/*epidemiology
MH  - Risk
MH  - Schizophrenia/complications/*epidemiology
PMC - PMC6998133
EDAT- 2012/11/24 06:00
MHDA- 2013/03/19 06:00
PMCR- 2012/07/30
CRDT- 2012/11/24 06:00
PHST- 2012/11/24 06:00 [entrez]
PHST- 2012/11/24 06:00 [pubmed]
PHST- 2013/03/19 06:00 [medline]
PHST- 2012/07/30 00:00 [pmc-release]
AID - S204579601200042X [pii]
AID - 00042 [pii]
AID - 10.1017/S204579601200042X [doi]
PST - ppublish
SO  - Epidemiol Psychiatr Sci. 2012 Dec;21(4):335-42. doi: 10.1017/S204579601200042X.