PMID- 23185086
OWN - NLM
STAT- MEDLINE
DCOM- 20130124
LR  - 20131213
IS  - 1550-0594 (Print)
IS  - 1550-0594 (Linking)
VI  - 43
IP  - 4
DP  - 2012 Oct
TI  - EEG current source density and the phenomenology of the default network.
PG  - 257-67
LID - 10.1177/1550059412449780 [doi]
AB  - In recent years, there has been an increasing line of research dedicated to the 
      investigation of the default mode network (DMN) of the brain and resting state 
      networks. However, the mental activity of the DMN has not been rigorously 
      assessed to date. The specific aims of the current study were 2-fold: First, we 
      sought to determine whether the current source density (CSD) levels in the DMN 
      would correspond to other neuroimaging techniques. Second, we sought to 
      understand the subjective mental activity of the DMN during baseline recordings. 
      This study was conducted with 63 nonclinical participants, 34 female and 29 males 
      with a mean age of 19.2 years (standard deviation = 2.0). The participants were 
      recorded in 8 conditions. First, 4-minute eyes-closed baseline (ECB) and 
      eyes-opened baseline (EOB) were obtained. The participants then completed 3 
      assessment instruments and 3 image conditions while the electroencephalography 
      (EEG) was continuously recorded. Participants completed subjective reports for 
      baselines and image conditions. These were rated by 3 independent raters and 
      compared for reliability using a random effects model with an absolute agreement 
      definition. The mean CSD between all conditions differed significantly, in many 
      but not all regions of interest in the DMN. Interestingly, as suggested by other 
      studies, the DMN appears preferential to self-relevant, self-specific, or 
      self-perceptive processes. The reliability analyses show alpha for interrater 
      agreement for ECB at .95 and EOB at .96. The subjective reports obtained from the 
      participants regarding the mental activities employed during baseline recordings 
      correspond to attentional and self-regulatory processes, which may also implicate 
      the resting state or DMN as playing a direct role in the maintenance of a complex 
      behavior (eg, being still, attending, and self-regulating). Thus, attention and 
      self-regulation constitute the phenomenology of the resting state (DMN) in this 
      study. The results also demonstrate that EEG CSD is a useful method to examine 
      the DMN during concept-specific tasks to elucidate the neural activity associated 
      with these concepts. Standardized low-resolution electromagnetic tomography 
      (sLORETA) can localize to 5 mm(3), which is comparable to the findings in 
      functional magnetic resonance imaging (fMRI). However, sLORETA can provide data 
      about the difference in activity between groups, individuals, or populations 
      which in many cases fMRI cannot provide.
FAU - Cannon, Rex L
AU  - Cannon RL
AD  - Department of Psychology, Clinical Neuroscience, Self-regulation and Biological 
      Psychology Laboratory, University of Tennessee, Knoxville, TN 37996, USA. 
      rcannon2@utk.edu
FAU - Baldwin, Debora R
AU  - Baldwin DR
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Clin EEG Neurosci
JT  - Clinical EEG and neuroscience
JID - 101213033
SB  - IM
MH  - Adolescent
MH  - Anxiety/physiopathology
MH  - Brain/*physiology
MH  - Brain Mapping/*methods
MH  - Cognition/*physiology
MH  - Depression/physiopathology
MH  - Electroencephalography/*methods
MH  - Emotions/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Nerve Net/*physiology
MH  - Young Adult
EDAT- 2012/11/28 06:00
MHDA- 2013/01/25 06:00
CRDT- 2012/11/28 06:00
PHST- 2012/11/28 06:00 [entrez]
PHST- 2012/11/28 06:00 [pubmed]
PHST- 2013/01/25 06:00 [medline]
AID - 43/4/257 [pii]
AID - 10.1177/1550059412449780 [doi]
PST - ppublish
SO  - Clin EEG Neurosci. 2012 Oct;43(4):257-67. doi: 10.1177/1550059412449780.