PMID- 23185762
OWN - NLM
STAT- MEDLINE
DCOM- 20140102
LR  - 20161018
IS  - 1003-5370 (Print)
IS  - 1003-5370 (Linking)
VI  - 32
IP  - 9
DP  - 2012 Sep
TI  - [Effects of yiqi huoxue qufeng decoction on the diamine oxidase and immunoglobin 
      E of patients with chronic urticaria].
PG  - 1216-8
AB  - OBJECTIVE: To observe effects of Yiqi Huoxue Qufeng Decoction (YHQD, with the 
      actions of replenishing qi, activating blood, and dispelling wind) on diamine 
      oxidase (DAO) and immunoglobulin E (IgE) of patients with chronic urticaria. 
      METHODS: Eighty-five chronic urticaria patients from the clinics of dermatology, 
      Shaanxi Hospital of Traditional Chinese Medicine were randomly assigned to the 
      treatment group (50 cases) and the control group (35 cases). Besides, another 15 
      healthy volunteers were recruited as the healthy group. Patients in the treatment 
      group took YHQD, one dose daily, once in the morning and once in the evening. 
      Patients in the control group took Fuyang Granule (FYG), 6 g each time, three 
      times daily. The therapeutic course for the two groups was 8 weeks. The effective 
      rates of the two groups were observed after treatment and 2 months after quitting 
      treatment. The levels of DAO and IgE were observed in the three groups before and 
      after treatment. RESULTS: The post-treatment recovery rate (20 cases, 44.0%) and 
      the effective rate 2 months after quitting treatment (62.0%) were higher in the 
      treatment group than in the control group (7 cases, 20.0%; 31.4%) with 
      statistical difference (P<0.05). The DAO level in the two treatment groups (6.9 
      +/- 1.8 in the treatment group and 6.5 +/- 1.8 in the control group) was 
      obviously higher than that in the healthy group (1.1 +/- 0.4), showing 
      statistical difference (P<0.05). The post-treatment DAO and IgE both decreased in 
      the treatment group and the control group when compared with before treatment in 
      the same group. Those were lower in the treatment group than in the control group 
      with statistical difference (P<0.05). CONCLUSION: YHQD could improve the symptoms 
      of chronic urticaria patients, ameliorate the intestines mucosa barrier function 
      and the immunity.
FAU - Wu, Cai-Xia
AU  - Wu CX
AD  - Department of Dermatology, Shaanxi Hospital of Traditional Chinese Medicine, 
      Xi'an 710003. wucx12187@sina.com
FAU - Li, Na
AU  - Li N
FAU - Xu, Zhan-Hong
AU  - Xu ZH
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhongguo Zhong Xi Yi Jie He Za Zhi
JT  - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese 
      journal of integrated traditional and Western medicine
JID - 9211576
RN  - 0 (Drugs, Chinese Herbal)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 82249-55-6 (yiki-huoxue)
RN  - EC 1.4.3.21 (Amine Oxidase (Copper-Containing))
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Amine Oxidase (Copper-Containing)/*blood
MH  - Case-Control Studies
MH  - Chronic Disease
MH  - Drugs, Chinese Herbal/*therapeutic use
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - Middle Aged
MH  - *Phytotherapy
MH  - Treatment Outcome
MH  - Urticaria/blood/*drug therapy
MH  - Young Adult
EDAT- 2012/11/29 06:00
MHDA- 2014/01/03 06:00
CRDT- 2012/11/29 06:00
PHST- 2012/11/29 06:00 [entrez]
PHST- 2012/11/29 06:00 [pubmed]
PHST- 2014/01/03 06:00 [medline]
PST - ppublish
SO  - Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Sep;32(9):1216-8.