PMID- 23186081
OWN - NLM
STAT- MEDLINE
DCOM- 20140929
LR  - 20131202
IS  - 1445-2197 (Electronic)
IS  - 1445-1433 (Linking)
VI  - 83
IP  - 12
DP  - 2013 Dec
TI  - Survival outcome in New Zealand after resection of colorectal cancer lung 
      metastases.
PG  - 959-62
LID - 10.1111/ans.12012 [doi]
AB  - BACKGROUND: Colorectal cancer is the second most common type of solid organ 
      cancer in New Zealand behind prostate cancer. Even with treatment, distant 
      disease may develop in the liver and lungs. Surgical resection of isolated liver 
      and/or lung metastasis is now commonly considered, but survival outcomes from the 
      latter are not well described. This study aims to review the 5-year survival and 
      prognostic factors of patients who have resection for lung metastasis of 
      colorectal origin. METHODS: A retrospective audit of surgical resection for lung 
      metastasis performed by thoracic departments of several tertiary referral centres 
      within New Zealand was performed. The study period was between 1997 and 2011. 
      Patients were identified through operative logs, audit databases, clinical case 
      mix codes and pathology databases. Patient demographics, preoperative and 
      post-operative variables were recorded. All patients were followed up for 
      survival analysis. Mann-Whitney and chi-square tests were performed for data 
      analysis. A P-value of less than 0.05 was significant. RESULTS: There were 106 
      (59 male) patients. Median age was 64 (inter-quartile range (IQR) 57-73) years. 
      Median follow-up period was 30 (IQR 16-46) months. The 5-year overall and 
      cancer-specific survival was 40% and 43%, respectively. The only good prognostic 
      factor for survival after lung resection was a long disease-free interval (P = 
      0.04) between surgery for the colorectal primary and lung metastasis. CONCLUSION: 
      Lung resection for isolated colorectal metastases provides a reasonable 5-year 
      survival. Outcomes from lung resection for colorectal metastases in New Zealand 
      are comparable to that from international series.
CI  - (c) 2012 The Authors. ANZ Journal of Surgery (c) 2012 Royal Australasian College of 
      Surgeons.
FAU - Goonerante, Dinuk
AU  - Goonerante D
AD  - Colorectal Unit, Department of Surgery, Christchurch Hospital, Christchurch, New 
      Zealand.
FAU - Gray, Chris
AU  - Gray C
FAU - Lim, Michael
AU  - Lim M
FAU - Dixon, Liane
AU  - Dixon L
FAU - Dobbs, Bruce
AU  - Dobbs B
FAU - Wakeman, Chris
AU  - Wakeman C
FAU - Frizelle, Frank
AU  - Frizelle F
CN  - Colorectal Lung Metastases Research Group (CRLMRG)
LA  - eng
PT  - Journal Article
DEP - 20121127
PL  - Australia
TA  - ANZ J Surg
JT  - ANZ journal of surgery
JID - 101086634
SB  - IM
MH  - Aged
MH  - Colonic Neoplasms/surgery
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Lung Neoplasms/*mortality/secondary/*surgery
MH  - Male
MH  - Middle Aged
MH  - New Zealand/epidemiology
MH  - Pneumonectomy
MH  - Prognosis
MH  - Rectal Neoplasms/surgery
MH  - Retrospective Studies
MH  - Time Factors
OTO - NOTNLM
OT  - colorectal cancer
OT  - pulmonary metastases
FIR - Goonerante, D
IR  - Goonerante D
FIR - Dixon, L
IR  - Dixon L
FIR - Lim, M
IR  - Lim M
FIR - Gray, C
IR  - Gray C
FIR - Wakeman, C
IR  - Wakeman C
FIR - Dobbs, B
IR  - Dobbs B
FIR - Frizelle, F
IR  - Frizelle F
FIR - Thompson-Fawcett, Mark
IR  - Thompson-Fawcett M
FIR - Ho, Christine
IR  - Ho C
FIR - Bissett, Ian
IR  - Bissett I
FIR - van den Heever, Ursula
IR  - van den Heever U
FIR - Dennett, Elizabeth
IR  - Dennett E
FIR - Reddy, Sumeet
IR  - Reddy S
FIR - Lolohea, Simione
IR  - Lolohea S
FIR - Van Dalen, Ralph
IR  - Van Dalen R
FIR - Delasau, Ilaita
IR  - Delasau I
FIR - Singh, Harsh
IR  - Singh H
EDAT- 2012/11/29 06:00
MHDA- 2014/09/30 06:00
CRDT- 2012/11/29 06:00
PHST- 2012/10/20 00:00 [accepted]
PHST- 2012/11/29 06:00 [entrez]
PHST- 2012/11/29 06:00 [pubmed]
PHST- 2014/09/30 06:00 [medline]
AID - 10.1111/ans.12012 [doi]
PST - ppublish
SO  - ANZ J Surg. 2013 Dec;83(12):959-62. doi: 10.1111/ans.12012. Epub 2012 Nov 27.