PMID- 23192460 OWN - NLM STAT- MEDLINE DCOM- 20130812 LR - 20220801 IS - 1432-1076 (Electronic) IS - 0340-6199 (Linking) VI - 172 IP - 3 DP - 2013 Mar TI - Maculopapular rash in the convalescent phase of Kawasaki disease: case series and literature review. PG - 405-7 LID - 10.1007/s00431-012-1898-y [doi] AB - Intravenous immunoglobulin (IVIG) is currently the standard treatment for Kawasaki disease (KD). Although IVIG therapy is generally well tolerated, several minor adverse reactions have been reported. We report a patient with KD treated with IVIG, who developed a cutaneous reaction in the convalescent phase (approximately 10 days after therapy). We identified seven additional KD cases with a similar presentation, accounting for 9.3 % of KD patients at our hospital. We performed a literature review and found that a maculopapular rash could be observed approximately 10 days after IVIG treatment, in patients with and those without KD. CONCLUSION: Maculopapular rash can occur in nearly 10 % of IVIG-treated children with KD in our cohort, approximately 10 days after treatment. A delayed-onset adverse event of IVIG could be a causative etiology of this unrecognized eruption. FAU - Takeuchi, Masato AU - Takeuchi M AD - Department of Pediatrics, Chigasaki Municipal Hospital, Honson 5-15-1, Chigasaki, Kanagawa, Japan. masatotakeuchi@gmail.com FAU - Oda, Yoichiro AU - Oda Y FAU - Suzuki, Isao AU - Suzuki I LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20121129 PL - Germany TA - Eur J Pediatr JT - European journal of pediatrics JID - 7603873 RN - 0 (Immunoglobulins, Intravenous) RN - 0 (Immunologic Factors) SB - IM MH - Child, Preschool MH - Convalescence MH - Drug Eruptions/*diagnosis/etiology MH - Female MH - Humans MH - Immunoglobulins, Intravenous/*adverse effects/therapeutic use MH - Immunologic Factors/*adverse effects/therapeutic use MH - Infant MH - Male MH - Mucocutaneous Lymph Node Syndrome/*drug therapy EDAT- 2012/11/30 06:00 MHDA- 2013/08/13 06:00 CRDT- 2012/11/30 06:00 PHST- 2012/08/23 00:00 [received] PHST- 2012/11/15 00:00 [accepted] PHST- 2012/11/14 00:00 [revised] PHST- 2012/11/30 06:00 [entrez] PHST- 2012/11/30 06:00 [pubmed] PHST- 2013/08/13 06:00 [medline] AID - 10.1007/s00431-012-1898-y [doi] PST - ppublish SO - Eur J Pediatr. 2013 Mar;172(3):405-7. doi: 10.1007/s00431-012-1898-y. Epub 2012 Nov 29.