PMID- 23195378
OWN - NLM
STAT- MEDLINE
DCOM- 20130826
LR  - 20220318
IS  - 1532-8198 (Electronic)
IS  - 1092-9134 (Linking)
VI  - 17
IP  - 2
DP  - 2013 Apr
TI  - Carcinoma of the fallopian tube: Results of a multi-institutional retrospective 
      analysis of 127 patients with evaluation of staging and prognostic factors.
PG  - 159-64
LID - S1092-9134(12)00127-X [pii]
LID - 10.1016/j.anndiagpath.2012.10.001 [doi]
AB  - The aim of this study was to determine the impact of prognostic factors in 
      primary fallopian tube carcinoma (PFTC). All cases of PFTC diagnosed between 1990 
      and 2010 were retrieved from the files of 6 academic centers. The cases were 
      staged according to a modification of the International Federation of Obstetrics 
      and Gynecology staging system proposed by Alvarado-Cabrero et al (Gynecol Oncol 
      1999; 72: 367-379). One hundred twenty-seven PFTC cases were identified. The mean 
      age of the patients was 64.2 years. Stage distribution was as follows: 72 (57%), 
      stage I; 19 (15%), stage II; 28 (22%), stage III; and 8 (6.2%), stage IV. Depth 
      of infiltration of the tubal wall was an independent prognostic factor in stage I 
      cases (P < .001). Carcinomas located in the fimbriated end even without invasion 
      had a worse prognosis than did carcinomas involving the tubal portion of the 
      organ. The presence of vascular space invasion correlated with the depth of tubal 
      wall invasion (P = .001) and the presence of lymph node metastases (P = .003). 
      Tumor grade significantly correlated with survival (P < .0001), but histologic 
      type was of marginal significance and only if it was grouped as 
      nonserous/non-clear cell vs serous/clear cell (P = .04). The depth of invasion of 
      the tubal wall and the presence of carcinoma in the fimbriated end even without 
      invasion are important prognostic indicators. The modified International 
      Federation of Obstetrics and Gynecology staging system should be used on a 
      routine basis in all carcinomas of the fallopian tube.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - Alvarado-Cabrero, Isabel
AU  - Alvarado-Cabrero I
AD  - Department of Pathology, Hospital de Oncologia, Centro Medico Nacional, IMSS, CMN 
      Siglo XXI, Mexico City, DF 06720, Mexico. keme2.tijax12@gmail.com
FAU - Stolnicu, Simona
AU  - Stolnicu S
FAU - Kiyokawa, Takako
AU  - Kiyokawa T
FAU - Yamada, Kyosuke
AU  - Yamada K
FAU - Nikaido, Takashi
AU  - Nikaido T
FAU - Santiago-Payan, Hector
AU  - Santiago-Payan H
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20121126
PL  - United States
TA  - Ann Diagn Pathol
JT  - Annals of diagnostic pathology
JID - 9800503
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma/*classification/*pathology
MH  - Fallopian Tube Neoplasms/*classification/*pathology
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Neoplasm Grading
MH  - Neoplasm Staging/*methods
MH  - Prognosis
MH  - Retrospective Studies
EDAT- 2012/12/01 06:00
MHDA- 2013/08/27 06:00
CRDT- 2012/12/01 06:00
PHST- 2012/07/14 00:00 [received]
PHST- 2012/09/19 00:00 [revised]
PHST- 2012/10/04 00:00 [accepted]
PHST- 2012/12/01 06:00 [entrez]
PHST- 2012/12/01 06:00 [pubmed]
PHST- 2013/08/27 06:00 [medline]
AID - S1092-9134(12)00127-X [pii]
AID - 10.1016/j.anndiagpath.2012.10.001 [doi]
PST - ppublish
SO  - Ann Diagn Pathol. 2013 Apr;17(2):159-64. doi: 10.1016/j.anndiagpath.2012.10.001. 
      Epub 2012 Nov 26.