PMID- 23196574
OWN - NLM
STAT- MEDLINE
DCOM- 20140421
LR  - 20190918
IS  - 1882-0654 (Electronic)
IS  - 0009-918X (Linking)
VI  - 52
IP  - 11
DP  - 2012
TI  - [Neuro-Behcet disease and neuro-Sweet disease].
PG  - 1234-6
AB  - Behcet disease and Sweet disease are multisystem inflammatory disorders involving 
      mucocutaneous tissue as well as nervous system (neuro-Behcet disease and 
      neuro-Sweet disease). Pathological findings in the encephalitis are chiefly 
      perivascular cuffing of small venules by neutrophils, T lymphocytes, and 
      macrphages. Destruction of the brain substrates is mild in neuro-Sweet disease 
      compared with that of neuro-Behcet disease, especially that of chronic 
      progressive subtype. HLA (human leukocyte antigen)-B51 is frequently positive in 
      neuro-Behcet disease, and the frequencies of HLA-B54 and Cw1 in neuro-Sweet 
      disease are significantly higher than not only those in Japanese normal controls 
      but also those in patients with these diseases without nervous complications. 
      These HLA types are considered as risk factors which are directly associated with 
      the etiology of these diseases. Prednisolone is usually used for the treatment of 
      acute phase of both diseases. Methotrexate and infliximab are administered to 
      patients with the chronic progressive type of neuro-Behcet disease. Colchicine 
      and dapsone are prescribed to prednisolone-dependent recurrent cases of 
      neuro-Sweet disease.
FAU - Hisanaga, Kinya
AU  - Hisanaga K
AD  - Department of Neurology, Miyagi National Hospital.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
SB  - IM
MH  - Adult
MH  - Behcet Syndrome/*complications
MH  - Female
MH  - Humans
MH  - Male
MH  - Nervous System Diseases/*complications
MH  - Sweet Syndrome/*complications
EDAT- 2012/12/01 06:00
MHDA- 2014/04/22 06:00
CRDT- 2012/12/01 06:00
PHST- 2012/12/01 06:00 [entrez]
PHST- 2012/12/01 06:00 [pubmed]
PHST- 2014/04/22 06:00 [medline]
AID - DN/JST.JSTAGE/clinicalneurol/52.1234 [pii]
AID - 10.5692/clinicalneurol.52.1234 [doi]
PST - ppublish
SO  - Rinsho Shinkeigaku. 2012;52(11):1234-6. doi: 10.5692/clinicalneurol.52.1234.