PMID- 23197073 OWN - NLM STAT- MEDLINE DCOM- 20130916 LR - 20231213 IS - 1753-4666 (Electronic) IS - 1753-4658 (Linking) VI - 7 IP - 2 DP - 2013 Apr TI - Correlation of symptoms with total IgE and specific IgE levels in patients presenting with allergic rhinitis. PG - 75-9 LID - 10.1177/1753465812468500 [doi] AB - OBJECTIVE: The objective of this study was to investigate the correlation of symptoms in patients with presumed allergic rhinitis on the basis of their medical history and physical examination with the levels of total immunoglobulin E (IgE) and specific IgE, and to question the necessity of these tests in diagnosis. METHODS: The records of 295 patients, who had at least two complaints of nasal itching, nasal obstruction, runny discharge and sneezing, and/or presumed as allergic rhinitis on physical examination findings were retrospectively screened. The correlation between the levels of IgE, specific inhalant IgE, and food-specific serum IgE were evaluated in these patients. RESULTS: A total of 70 cases (23.7%) were determined to have a total value of IgE under 20 U/ml, 113 cases (38.3%) with IgE values between 20 U/ml and 100 U/ml, and 100 cases with IgE values above 100 U/ml. Results of total IgE could not be obtained in 12 (4.06%) patients. Dermatophagoides farinae was the most common allergy in this group with 74 (68.5%) cases. CONCLUSIONS: The determination of IgE in allergic rhinitis is a supportive method. However, it cannot be recommended for routine use because of the time loss and high cost. FAU - Karli, Rifat AU - Karli R AD - Department of Otorhinolaryngology, School of Medicine, Ondokuz Mayis University, KBB klinigi, Samsun, Turkey. rifatkarli@yahoo.com FAU - Balbaloglu, Evrim AU - Balbaloglu E FAU - Uzun, Lokman AU - Uzun L FAU - Cinar, Fikret AU - Cinar F FAU - Ugur, Mehmet Birol AU - Ugur MB LA - eng PT - Journal Article DEP - 20121129 PL - England TA - Ther Adv Respir Dis JT - Therapeutic advances in respiratory disease JID - 101316317 RN - 0 (Antigens, Dermatophagoides) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Antigens, Dermatophagoides/immunology MH - Child MH - Female MH - Humans MH - Immunoglobulin E/*analysis/blood MH - Male MH - Middle Aged MH - Retrospective Studies MH - Rhinitis, Allergic, Perennial/diagnosis/*immunology/microbiology MH - Glycine max/immunology MH - Young Adult EDAT- 2012/12/01 06:00 MHDA- 2013/09/17 06:00 CRDT- 2012/12/01 06:00 PHST- 2012/12/01 06:00 [entrez] PHST- 2012/12/01 06:00 [pubmed] PHST- 2013/09/17 06:00 [medline] AID - 1753465812468500 [pii] AID - 10.1177/1753465812468500 [doi] PST - ppublish SO - Ther Adv Respir Dis. 2013 Apr;7(2):75-9. doi: 10.1177/1753465812468500. Epub 2012 Nov 29.