PMID- 23197465
OWN - NLM
STAT- MEDLINE
DCOM- 20140605
LR  - 20211021
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Print)
IS  - 1053-1807 (Linking)
VI  - 38
IP  - 5
DP  - 2013 Nov
TI  - Respiratory bellows-gated late gadolinium enhancement of the left atrium.
PG  - 1210-4
LID - 10.1002/jmri.23954 [doi]
AB  - PURPOSE: To compare bellows-gated late gadolinium enhancement (LGE) with standard 
      navigator-gated (NAV-gated) LGE for left atrial (LA) imaging, to eliminate the 
      inflow artifacts associated with NAV-gating. MATERIALS AND METHODS: Eleven 
      subjects, including six patients with atrial fibrillation (AF), were imaged with 
      a 3D free-breathing NAV-gated and bellows-gated LGE. Motion compensation was 
      compared by blinded grading of image sharpness and motion ghosting (0 = worst, 2 
      = best). Inflow artifacts in the right inferior pulmonary vein (RIPV) and right 
      superior PV (RSPV) were characterized on the same scale (0 = none, 2 = 
      prominent). In patients, each PV was divided into four quadrants 
      circumferentially in order to assess agreement about scar presence on both image 
      sets. RESULTS: Respiratory compensation was not different (1.7 +/- 0.5 vs. 1.6 +/- 
      0.5, sharpness, 1.6 +/- 0.5 vs. 1.6 +/- 0.5, ghosting, P = NS) for bellows- and 
      NAV-gated images. For NAV-gated LGE, inflow artifacts were more prominent in the 
      RSPV than the RIPV (1.2 +/- 0.8 vs. 0.7 +/- 0.5, P = 0.046). Visually, inflow 
      artifacts both obscured and mimicked the true scar. Disagreement on the presence 
      of scar was found in 18% of the assessed quadrants, with 25% disagreement for 
      RSPV quadrants (P = 0.01). CONCLUSION: Bellows-gated LGE provides similar 
      respiratory compensation as NAV-gating, without inflow artifacts, leading to 
      improved assessment of scar presence.
CI  - Copyright (c) 2013 Wiley Periodicals, Inc.
FAU - Peters, Dana C
AU  - Peters DC
AD  - Beth Israel Deaconess Medical Center, Department of Medicine (Cardiovascular 
      Division), Boston, Massachusetts, USA; Department of Medicine, Harvard Medical 
      School, Boston, Massachusetts, USA; Department of Diagnostic Radiology, Yale 
      Medical School, New Haven, Connecticut, USA.
FAU - Shaw, Jaime L
AU  - Shaw JL
FAU - Knowles, Benjamin R
AU  - Knowles BR
FAU - Moghari, Mehdi Hedjazi
AU  - Moghari MH
FAU - Manning, Warren J
AU  - Manning WJ
LA  - eng
GR  - R21 HL098573/HL/NHLBI NIH HHS/United States
GR  - R21 HL103463/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20121129
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Atrial Fibrillation/*pathology
MH  - Contrast Media
MH  - Female
MH  - *Gadolinium DTPA
MH  - Heart Atria/*pathology
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Respiratory-Gated Imaging Techniques/*methods
MH  - Sensitivity and Specificity
PMC - PMC3812253
MID - NIHMS415791
OTO - NOTNLM
OT  - NAV-gating
OT  - artifacts
OT  - atrial fibrillation
OT  - bellows
OT  - late gadolinium enhancement
OT  - respiratory compensation
EDAT- 2012/12/01 06:00
MHDA- 2014/06/06 06:00
PMCR- 2014/11/01
CRDT- 2012/12/01 06:00
PHST- 2012/01/29 00:00 [received]
PHST- 2012/10/10 00:00 [accepted]
PHST- 2012/12/01 06:00 [entrez]
PHST- 2012/12/01 06:00 [pubmed]
PHST- 2014/06/06 06:00 [medline]
PHST- 2014/11/01 00:00 [pmc-release]
AID - 10.1002/jmri.23954 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2013 Nov;38(5):1210-4. doi: 10.1002/jmri.23954. Epub 2012 
      Nov 29.