PMID- 23198139 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121203 LR - 20211021 IS - 2090-0430 (Electronic) IS - 2090-0422 (Print) IS - 2090-0430 (Linking) VI - 2012 DP - 2012 TI - Linkage of multiple sclerosis and guillain-barre syndrome: a population-based survey in isfahan, iran. PG - 232139 LID - 10.1155/2012/232139 [doi] LID - 232139 AB - Background. Multiple Sclerosis (MS) and Guillain Barre Syndrome (GBS) are autoimmune demyelinating disorders of Central and Peripheral Nervous system, respectively. The coexistence of these two syndromes in an individual's life span is rare. Objectives. To inspect throughout Isfahan MS society (IMSS) records for MS cases who had history of documented GBS whether before the onset of MS or after it. Methods. This retrospective survey was carried out by analyzing the clinical records of 3,522 MS patients who were registered with IMSS, from April 2003 to July 2010. Eligible cases were requested to attend to IMSS for final clinical/paraclinical examinations. Results. Among 3,522 (2,716 women and 806 men) MS subjects, we could identify seven patients (six females and one male) with documented diagnosis of GBS. Six patients (five women and one man) had developed MS within 6.5 +/- 7.0 (range: 1-16) years after being diagnosed with GBS and one (a woman) had developed GBS three years after the diagnosis of MS. Conclusion. It seems that the development of MS in individuals with history of GBS is more than a simple incidental event. FAU - Etemadifar, Masoud AU - Etemadifar M AD - Department of Neurology, Medical School, Isfahan University of Medical Sciences, Isfahan 81744-176, Iran ; Medical School, Isfahan University of Medical Sciences, Isfahan 81744-176, Iran. FAU - Roomizadeh, Peyman AU - Roomizadeh P FAU - Abtahi, Seyed-Hossein AU - Abtahi SH FAU - Sajjadi, Sepideh AU - Sajjadi S FAU - Abedini, Amin AU - Abedini A FAU - Golabbakhsh, Aryan AU - Golabbakhsh A FAU - Fereidan-Esfahani, Mahboobeh AU - Fereidan-Esfahani M FAU - Akbari, Mojtaba AU - Akbari M LA - eng PT - Journal Article DEP - 20121104 PL - United States TA - Autoimmune Dis JT - Autoimmune diseases JID - 101546750 PMC - PMC3501815 EDAT- 2012/12/01 06:00 MHDA- 2012/12/01 06:01 PMCR- 2012/11/04 CRDT- 2012/12/01 06:00 PHST- 2012/06/02 00:00 [received] PHST- 2012/10/01 00:00 [revised] PHST- 2012/10/02 00:00 [accepted] PHST- 2012/12/01 06:00 [entrez] PHST- 2012/12/01 06:00 [pubmed] PHST- 2012/12/01 06:01 [medline] PHST- 2012/11/04 00:00 [pmc-release] AID - 10.1155/2012/232139 [doi] PST - ppublish SO - Autoimmune Dis. 2012;2012:232139. doi: 10.1155/2012/232139. Epub 2012 Nov 4.