PMID- 23200784
OWN - NLM
STAT- MEDLINE
DCOM- 20130909
LR  - 20211021
IS  - 1878-9307 (Electronic)
IS  - 1878-9293 (Print)
IS  - 1878-9293 (Linking)
VI  - 4
DP  - 2013 Apr
TI  - Training-associated changes and stability of attention bias in youth: 
      Implications for Attention Bias Modification Treatment for pediatric anxiety.
PG  - 52-64
LID - S1878-9293(12)00084-9 [pii]
LID - 10.1016/j.dcn.2012.11.001 [doi]
AB  - Attention Bias Modification Treatment (ABMT), an emerging treatment for anxiety 
      disorders, is thought to modify underlying, stable patterns of attention. 
      Therefore, ABMT research should take into account the impact of attention bias 
      stability on attention training response, especially in pediatric populations. 
      ABMT research typically relies on the dot-probe task, where individuals detect a 
      probe following an emotional-neutral stimulus pair. The current research presents 
      two dot-probe experiments relevant to ABMT and attention-bias stability. In 
      Experiment 1, anxious youth receiving 8-weeks of cognitive-behavioral therapy 
      (CBT) were randomly assigned to ABMT that trains attention towards happy faces 
      (n=18) or placebo (n=18). Two additional comparison groups, anxious youth 
      receiving only CBT (n=17) and healthy comparison youth (n=16), were studied. 
      Active attention training towards happy faces did not augment clinician-rated 
      response to CBT; however, individuals receiving training exhibited reductions on 
      self-report measures of anxiety earlier than individuals receiving CBT only. In 
      Experiment 2, healthy youth (n=12) completed a dot-probe task twice while 
      undergoing functional magnetic resonance imaging. Intra-class correlation 
      demonstrated stability of neural activation in response to attention bias in the 
      ventrolateral prefrontal cortex and amygdala. Together, these two studies 
      investigate the ways in which attention-bias stability may impact future work on 
      ABMT.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Britton, Jennifer C
AU  - Britton JC
AD  - Section on Development and Affective Neuroscience, National Institute of Mental 
      Health (NIMH), 9000 Rockville Pike, Building 15K, Bethesda, MD 20892, USA. 
      j.britton@miami.edu
FAU - Bar-Haim, Yair
AU  - Bar-Haim Y
FAU - Clementi, Michelle A
AU  - Clementi MA
FAU - Sankin, Lindsey S
AU  - Sankin LS
FAU - Chen, Gang
AU  - Chen G
FAU - Shechner, Tomer
AU  - Shechner T
FAU - Norcross, Maxine A
AU  - Norcross MA
FAU - Spiro, Carolyn N
AU  - Spiro CN
FAU - Lindstrom, Kara M
AU  - Lindstrom KM
FAU - Pine, Daniel S
AU  - Pine DS
LA  - eng
GR  - K99 MH091183/MH/NIMH NIH HHS/United States
GR  - ImNIH/Intramural NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, N.I.H., Intramural
DEP - 20121110
PL  - Netherlands
TA  - Dev Cogn Neurosci
JT  - Developmental cognitive neuroscience
JID - 101541838
SB  - IM
MH  - Adolescent
MH  - Amygdala/physiology
MH  - Anxiety Disorders/*therapy
MH  - Attention/*physiology
MH  - Child
MH  - Cognitive Behavioral Therapy/*methods
MH  - Facial Expression
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Neuropsychological Tests
MH  - Pattern Recognition, Visual/physiology
MH  - Prefrontal Cortex/physiology
MH  - Self Report
MH  - Treatment Outcome
PMC - PMC3606014
MID - NIHMS421488
EDAT- 2012/12/04 06:00
MHDA- 2013/09/10 06:00
PMCR- 2012/11/10
CRDT- 2012/12/04 06:00
PHST- 2012/07/03 00:00 [received]
PHST- 2012/10/12 00:00 [revised]
PHST- 2012/11/02 00:00 [accepted]
PHST- 2012/12/04 06:00 [entrez]
PHST- 2012/12/04 06:00 [pubmed]
PHST- 2013/09/10 06:00 [medline]
PHST- 2012/11/10 00:00 [pmc-release]
AID - S1878-9293(12)00084-9 [pii]
AID - 10.1016/j.dcn.2012.11.001 [doi]
PST - ppublish
SO  - Dev Cogn Neurosci. 2013 Apr;4:52-64. doi: 10.1016/j.dcn.2012.11.001. Epub 2012 
      Nov 10.