PMID- 23203652
OWN - NLM
STAT- MEDLINE
DCOM- 20130923
LR  - 20211021
IS  - 1433-7339 (Electronic)
IS  - 0941-4355 (Linking)
VI  - 21
IP  - 5
DP  - 2013 May
TI  - The minimal clinical important difference in the World Health Organization 
      Quality of Life instrument--100.
PG  - 1295-301
LID - 10.1007/s00520-012-1664-8 [doi]
AB  - PURPOSE: The aim of this study was to estimate the minimal clinical important 
      difference (MCID) of the World Health Organization Quality of Life assessment 
      instrument (WHOQOL-100) for women with early-stage breast cancer. If the MCID is 
      known, then the instrument is also useful for individual patients and thus useful 
      in clinical practice. In this study, the MCID is the smallest change in quality 
      of life (QOL) scores considered clinically relevant for patients. METHODS: Data 
      were derived from a prospective study in which 223 women with early-stage breast 
      cancer and 383 women with benign breast problems completed the WHOQOL-100. MCID 
      values were determined by two distribution-based methods (0.5 standard deviation 
      (SD) and 1 standard error of measurement (SEM)) and an anchor-based method. 
      RESULTS: For 0.5 SD, MCID estimates ranged from 0.64 to 0.94, and for 1 SEM, MCID 
      estimates ranged from 0.69 to 1.18. The anchor-based approach resulted in MCID 
      estimates ranging from -1.56 to -0.71 for decline and from 0.51 to 1.27 for 
      improvement. CONCLUSION: A change in score of 1 on the WHOQOL-100 is proposed as 
      the MCID for women with early-stage breast cancer.
FAU - Den Oudsten, Brenda L
AU  - Den Oudsten BL
AD  - CoRPS-Center of Research on Psychology in Somatic Diseases, Department of Medical 
      Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, the 
      Netherlands. B.L.denOudsten@tilburguniversity.edu
FAU - Zijlstra, Wobbe P
AU  - Zijlstra WP
FAU - De Vries, Jolanda
AU  - De Vries J
LA  - eng
PT  - Journal Article
DEP - 20121201
PL  - Germany
TA  - Support Care Cancer
JT  - Supportive care in cancer : official journal of the Multinational Association of 
      Supportive Care in Cancer
JID - 9302957
SB  - IM
MH  - Adult
MH  - Aged
MH  - Breast Diseases/pathology/*psychology
MH  - Breast Neoplasms/pathology/*psychology
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Prospective Studies
MH  - *Quality of Life
MH  - World Health Organization
EDAT- 2012/12/04 06:00
MHDA- 2013/09/24 06:00
CRDT- 2012/12/04 06:00
PHST- 2012/06/05 00:00 [received]
PHST- 2012/11/19 00:00 [accepted]
PHST- 2012/12/04 06:00 [entrez]
PHST- 2012/12/04 06:00 [pubmed]
PHST- 2013/09/24 06:00 [medline]
AID - 10.1007/s00520-012-1664-8 [doi]
PST - ppublish
SO  - Support Care Cancer. 2013 May;21(5):1295-301. doi: 10.1007/s00520-012-1664-8. 
      Epub 2012 Dec 1.