PMID- 23206449
OWN - NLM
STAT- MEDLINE
DCOM- 20130725
LR  - 20170214
IS  - 1473-2300 (Electronic)
IS  - 0300-0605 (Linking)
VI  - 40
IP  - 5
DP  - 2012
TI  - Vaspin serum concentration in patients with type 2 diabetes and carotid plaque.
PG  - 1670-6
AB  - OBJECTIVE: To examine whether there is an association between the serum 
      concentration of vaspin and the presence of carotid plaque in early stage type 2 
      diabetes mellitus (T2DM). METHODS: Patients (n = 61) with T2DM within 3 years of 
      diagnosis were divided into those with and those without carotid plaque. Fasting 
      serum vaspin levels, measured by enzymelinked immunosorbent assay, and blood 
      pressure were compared between these two groups and also with an age-matched, 
      apparently healthy control group (n = 26). RESULTS: Fasting serum vaspin 
      concentrations were significantly higher in patients with T2DM without carotid 
      plaque than in controls, but significantly lower in T2DM patients with carotid 
      plaque than in those without. Multivariate logistic regression analysis showed a 
      significant positive association between the presence of carotid plaque and 
      systolic blood pressure and a significant inverse association between the 
      presence of carotid plaque and fasting serum vaspin concentration. CONCLUSION: A 
      significant inverse association was found, in patients with T2DM within 3 years 
      of diagnosis, between serum vaspin concentration and the presence of carotid 
      plaque.
FAU - Li, Z
AU  - Li Z
AD  - Department of Endocrinology, Fourth People's Hospital of Jinan City, Jinan, 
      China.
FAU - Ma, C
AU  - Ma C
FAU - Li, L
AU  - Li L
FAU - Pan, X
AU  - Pan X
FAU - Chen, L
AU  - Chen L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Int Med Res
JT  - The Journal of international medical research
JID - 0346411
RN  - 0 (SERPINA12 protein, human)
RN  - 0 (Serpins)
SB  - IM
MH  - Aged
MH  - Atherosclerosis/*blood/etiology/pathology
MH  - Carotid Artery Diseases/*blood/etiology/pathology
MH  - Carotid Intima-Media Thickness
MH  - Case-Control Studies
MH  - Diabetes Mellitus, Type 2/*blood/complications
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Risk Factors
MH  - Serpins/*blood
EDAT- 2012/12/05 06:00
MHDA- 2013/07/26 06:00
CRDT- 2012/12/05 06:00
PHST- 2012/12/05 06:00 [entrez]
PHST- 2012/12/05 06:00 [pubmed]
PHST- 2013/07/26 06:00 [medline]
AID - 10.1177/030006051204000506 [doi]
PST - ppublish
SO  - J Int Med Res. 2012;40(5):1670-6. doi: 10.1177/030006051204000506.