PMID- 23212800
OWN - NLM
STAT- MEDLINE
DCOM- 20130627
LR  - 20211021
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 251
IP  - 3
DP  - 2013 Mar
TI  - Sensitivity and specificity of monochromatic photography of the ocular fundus in 
      differentiating optic nerve head drusen and optic disc oedema: optic disc drusen 
      and oedema.
PG  - 923-8
LID - 10.1007/s00417-012-2223-1 [doi]
AB  - BACKGROUND: Evaluation of the efficacy of monochromatic photography of the ocular 
      fundus in differentiating optic nerve head drusen (ONHD) and optic disc oedema 
      (ODE). METHODS: Sixty-six patients with ONHD, 31 patients with ODE and 70 healthy 
      subjects were studied. Colour and monochromatic fundus photography with different 
      filters (green, red and autofluorescence) were performed. The results were 
      analysed blindly by two observers. The sensitivity, specificity and interobserver 
      agreement (k) of each test were assessed. RESULTS: Colour photography offers 65.5 
      % sensitivity and 100 % specificity for the diagnosis of ONHD. Monochromatic 
      photography improves sensitivity and specificity and provides similar results: 
      green filter (71.20 % sensitivity, 96.70 % specificity), red filter (80.30 % 
      sensitivity, 96.80 % specificity), and autofluorescence technique (87.8 % 
      sensitivity, 100 % specificity). The interobserver agreement was good with all 
      techniques used: autofluorescence (k = 0.957), green filter (k = 0.897), red 
      filter (k = 0.818) and colour (k = 0.809). CONCLUSIONS: Monochromatic fundus 
      photography permits ONHD and ODE to be differentiated, with good sensitivity and 
      very high specificity. The best results were obtained with autofluorescence and 
      red filter study.
FAU - Gili, Pablo
AU  - Gili P
AD  - Ophthalmology Unit, Alcorcon Foundation University Hospital, Madrid, Spain. 
      pgili@fhalcorcon.es
FAU - Flores-Rodriguez, Patricia
AU  - Flores-Rodriguez P
FAU - Yanguela, Julio
AU  - Yanguela J
FAU - Orduna-Azcona, Javier
AU  - Orduna-Azcona J
FAU - Martin-Rios, Maria Dolores
AU  - Martin-Rios MD
LA  - eng
PT  - Journal Article
DEP - 20121205
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - *Diagnostic Techniques, Ophthalmological
MH  - False Positive Reactions
MH  - Female
MH  - Fluorescein Angiography
MH  - *Fundus Oculi
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Observer Variation
MH  - Optic Disk Drusen/*diagnosis
MH  - Papilledema/*diagnosis
MH  - Photography/*instrumentation
MH  - Predictive Value of Tests
MH  - Sensitivity and Specificity
EDAT- 2012/12/06 06:00
MHDA- 2013/06/29 06:00
CRDT- 2012/12/06 06:00
PHST- 2012/07/26 00:00 [received]
PHST- 2012/11/20 00:00 [accepted]
PHST- 2012/10/26 00:00 [revised]
PHST- 2012/12/06 06:00 [entrez]
PHST- 2012/12/06 06:00 [pubmed]
PHST- 2013/06/29 06:00 [medline]
AID - 10.1007/s00417-012-2223-1 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):923-8. doi: 
      10.1007/s00417-012-2223-1. Epub 2012 Dec 5.