PMID- 23219662 OWN - NLM STAT- MEDLINE DCOM- 20130523 LR - 20181202 IS - 1090-2414 (Electronic) IS - 0147-6513 (Linking) VI - 88 DP - 2013 Feb TI - Organochlorine and organobromine compounds in a benthic fish (Solea solea) from Bizerte Lagoon (northern Tunisia): implications for human exposure. PG - 55-64 LID - S0147-6513(12)00395-8 [pii] LID - 10.1016/j.ecoenv.2012.10.021 [doi] AB - Information on the occurrence of persistent organic pollutants (POPs) in fish from Tunisia is scarce. In this study, thirty one persistent organic pollutants including organochlorine pesticides (OCPs) (dichlorodihenyltrichloroethane and its metabolites (DDTs), hexachlorocyclohexanes (HCHs) and hexachlorobenzene (HCB)), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and methoxylated polybrominated diphenyl ethers (MeO-PBDEs) were determined in solea solea muscle, from Bizerte Lagoon (northern Tunisia) and from the Mediterranean Sea (reference area) (northern Mediterranean). In the Bizerte Lagoon, contaminant concentrations generally followed this order: PCBs>DDTs>PBDEs>MeO-PBDEs>HCB>HCHs; while in the Mediterranean Sea, pollutant concentration followed this order: MeO-PBDEs>PCBs>DDTs>PBDEs>HCB>HCHs. Mean levels of organochlorine compounds were 1018 and 380 ng g(-1) lipid weight (lw) in fish from Bizerte Lagoon and the Mediterranean Sea, respectively. Mean concentrations of organobromine compounds were 279 and 301 ng g(-1) lw in sole from Bizerte Lagoon and the Mediterranean Sea, respectively. Organohalogen concentrations in fish from Bizerte Lagoon were similar or slightly lower than those reported for other marine fish species from other locations around the world. PCB, HCH, HCB and PBDE levels were negatively correlated with lipid content, while no such correlation was seen for DDTs. Assessment based on several available guidelines suggested an insignificant human health risk for dietary intake of HCB, lindane and PBDEs associated with consumption of sole. However, the estimated lifetime cancer risk from dietary exposure to DDTs and PCBs is a potential concern. CI - Copyright (c) 2012 Elsevier Inc. All rights reserved. FAU - Ben Ameur, Walid AU - Ben Ameur W AD - Laboratory of Environmental Analytical Chemistry (05/UR/12-03), University of Carthage, Faculty of Sciences, Bizerte 7021 Zarzouna, Tunisia. benameuroualid@yahoo.fr FAU - El Megdiche, Yassine AU - El Megdiche Y FAU - Eljarrat, Ethel AU - Eljarrat E FAU - Ben Hassine, Sihem AU - Ben Hassine S FAU - Badreddine, Barhoumi AU - Badreddine B FAU - Souad, Trabelsi AU - Souad T FAU - Bechir, Hammami AU - Bechir H FAU - Barcelo, Damia AU - Barcelo D FAU - Driss, Mohamed Ridha AU - Driss MR LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20121206 PL - Netherlands TA - Ecotoxicol Environ Saf JT - Ecotoxicology and environmental safety JID - 7805381 RN - 0 (Bromine Compounds) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Animals MH - Bromine Compounds/*analysis/metabolism MH - *Environmental Monitoring MH - Flatfishes/metabolism/*physiology MH - Food Chain MH - *Food Safety MH - Humans MH - Hydrocarbons, Chlorinated/*analysis/metabolism MH - Mediterranean Sea MH - Muscles/*chemistry MH - Risk Assessment MH - Tunisia MH - Water Pollutants, Chemical/*analysis/metabolism EDAT- 2012/12/12 06:00 MHDA- 2013/05/25 06:00 CRDT- 2012/12/11 06:00 PHST- 2012/03/28 00:00 [received] PHST- 2012/10/25 00:00 [revised] PHST- 2012/10/26 00:00 [accepted] PHST- 2012/12/11 06:00 [entrez] PHST- 2012/12/12 06:00 [pubmed] PHST- 2013/05/25 06:00 [medline] AID - S0147-6513(12)00395-8 [pii] AID - 10.1016/j.ecoenv.2012.10.021 [doi] PST - ppublish SO - Ecotoxicol Environ Saf. 2013 Feb;88:55-64. doi: 10.1016/j.ecoenv.2012.10.021. Epub 2012 Dec 6.