PMID- 23224674
OWN - NLM
STAT- MEDLINE
DCOM- 20130917
LR  - 20211021
IS  - 1433-9285 (Electronic)
IS  - 0933-7954 (Linking)
VI  - 48
IP  - 7
DP  - 2013 Jul
TI  - Childhood trauma, personality disorders symptoms and current major depressive 
      disorder in Togo.
PG  - 1095-103
LID - 10.1007/s00127-012-0634-2 [doi]
AB  - PURPOSE: Childhood trauma (CT) has been found to be associated with major 
      depressive disorder (MDD) and personality disorders (PD) in adulthood in Western 
      countries, but little is known about the relationship between CT, PD and MDD in 
      sub-Saharan Africa. The present study aims to examine: (1) the frequency of the 
      CT, (2) the association between CT, PD symptoms and MDD and (3) the mediating 
      role of PD between CT and MDD in Togo. METHODS: One hundred and eighty-one 
      participants (91 individuals with current MDD and 90 healthy controls without 
      psychiatric history) completed the 28-item CT Questionnaire (CTQ) and the 
      Personality Diagnostic Questionnaire (PDQ-4+). RESULTS: Participants in the MDD 
      group reported more frequently emotional, sexual and physical abuse and emotional 
      and physical neglect than controls (p < 0.001). There was a significant positive 
      correlation between the total abuse and the PDQ-4 + score (r = 0.48, p < 0.01) in 
      the total sample. Emotional and sexual abuses were associated with current MDD 
      and the number of PD criteria endorsed. Furthermore, PD symptoms mediated 
      partially the relationship between CT and current MDD. CONCLUSIONS: Our results 
      suggest an association between CT and current MDD in French-speaking sub-Saharan 
      Africa, and that this relationship may be explained by PD symptoms. Prospective 
      studies to confirm these results are warranted.
FAU - Kounou, Kossi B
AU  - Kounou KB
AD  - Universite de Toulouse, UPS, Laboratoire du Stress Traumatique (LST-EA 4560), CHU 
      de Toulouse, Hopital Casselardit, 170 av. de Casselardit, TSA 40031, 31059, 
      Toulouse Cedex 9, France.
FAU - Bui, Eric
AU  - Bui E
FAU - Dassa, Kolou S
AU  - Dassa KS
FAU - Hinton, Devon
AU  - Hinton D
FAU - Fischer, Laura
AU  - Fischer L
FAU - Djassoa, Gnansa
AU  - Djassoa G
FAU - Birmes, Philippe
AU  - Birmes P
FAU - Schmitt, Laurent
AU  - Schmitt L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121207
PL  - Germany
TA  - Soc Psychiatry Psychiatr Epidemiol
JT  - Social psychiatry and psychiatric epidemiology
JID - 8804358
SB  - IM
MH  - Adult
MH  - Child
MH  - Child Abuse/*psychology/statistics & numerical data
MH  - Comorbidity
MH  - Depressive Disorder, Major/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Personality Disorders/*epidemiology
MH  - Stress Disorders, Post-Traumatic/*epidemiology
MH  - Surveys and Questionnaires
MH  - Togo/epidemiology
MH  - Young Adult
EDAT- 2012/12/12 06:00
MHDA- 2013/09/18 06:00
CRDT- 2012/12/11 06:00
PHST- 2012/01/02 00:00 [received]
PHST- 2012/11/23 00:00 [accepted]
PHST- 2012/12/11 06:00 [entrez]
PHST- 2012/12/12 06:00 [pubmed]
PHST- 2013/09/18 06:00 [medline]
AID - 10.1007/s00127-012-0634-2 [doi]
PST - ppublish
SO  - Soc Psychiatry Psychiatr Epidemiol. 2013 Jul;48(7):1095-103. doi: 
      10.1007/s00127-012-0634-2. Epub 2012 Dec 7.