PMID- 23225643
OWN - NLM
STAT- MEDLINE
DCOM- 20140203
LR  - 20130712
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 38
IP  - 1
DP  - 2013 Jul
TI  - Assessment of left ventricular myocardial scar in coronary artery disease by a 
      three-dimensional MR imaging technique.
PG  - 72-9
LID - 10.1002/jmri.23962 [doi]
AB  - PURPOSE: To evaluate the feasibility of free-breathing three-dimensional (3D) 
      phase sensitive inversion recovery (PSIR) Turbo FLASH late gadolinium enhancement 
      (LGE) magnetic resonance images (MRI) on left ventricular scar in patients with 
      coronary artery disease (CAD) compared with clinically established breathhold 
      two-dimensional (2D) PSIR Turbo FLASH images. MATERIALS AND METHODS: In 58 
      consecutive patients with confirmed CAD, LGE MRI using the two sequences have 
      been acquired. Image quality was graded on a four-point scale according to the 
      image appearance. Qualitative evaluation including the distribution area and the 
      transmural extent of the scar based on the American Heart Association's (AHA's) 
      17-segment model was performed in both of 2D and 3D images. The scar volumes were 
      compared quantitatively between 2D and 3D images. RESULTS: A total of 51 
      individuals were used for final statistical analysis. No differences were noted 
      in image quality (P = 0.80), scar distribution area (P = 0.17), and scar 
      transmural extent (P = 0.20) between 3D and 2D images. There was strong 
      correlation in scar volume between the 3D and 2D results (r = 0.940; P < 0.001; Y 
      = 0.298 + 1.251X, R(2) = 0.876). But the scar volume derived from 3D images was 
      significantly larger than that derived from 2D images (2D versus 3D, 20.08 +/- 9.41 
      cm(3) versus 25.41 +/- 12.57 cm(3) , t = -7.60; P < 0.001). The trend toward a 
      larger scar volume identified by 3D method was indicated through Bland-Altman 
      analysis. CONCLUSION: Free-breathing 3D PSIR Turbo FLASH imaging is another 
      feasible method to identify left ventricular myocardial scar in patients with CAD 
      and detects more scar volume compared with breathhold 2D PSIR Turbo FLASH 
      imaging.
CI  - Copyright (c) 2012 Wiley Periodicals, Inc.
FAU - Yin, Gang
AU  - Yin G
AD  - Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing, China.
FAU - Zhao, Shihua
AU  - Zhao S
FAU - Lu, Minjie
AU  - Lu M
FAU - Ma, Ning
AU  - Ma N
FAU - Zuehlsdorff, Sven
AU  - Zuehlsdorff S
FAU - Cheng, Huaibing
AU  - Cheng H
FAU - Jiang, Shiliang
AU  - Jiang S
FAU - Zhao, Tao
AU  - Zhao T
FAU - Zhang, Yan
AU  - Zhang Y
FAU - An, Jing
AU  - An J
FAU - Lv, Chuanjian
AU  - Lv C
FAU - He, Zuoxiang
AU  - He Z
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121207
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
SB  - IM
MH  - Adult
MH  - Aged
MH  - Algorithms
MH  - Breath Holding
MH  - Cicatrix/etiology/*pathology
MH  - Coronary Artery Disease/complications/*pathology
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Image Enhancement/methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Imaging, Three-Dimensional/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Myocardial Stunning/etiology/*pathology
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Ventricular Dysfunction, Left/etiology/*pathology
OTO - NOTNLM
OT  - cardiovascular magnetic resonance
OT  - free-breathing
OT  - late gadolinium enhancement
OT  - phase sensitive inversion recovery
OT  - three-dimensional
EDAT- 2012/12/12 06:00
MHDA- 2014/02/04 06:00
CRDT- 2012/12/11 06:00
PHST- 2012/06/11 00:00 [received]
PHST- 2012/10/18 00:00 [accepted]
PHST- 2012/12/11 06:00 [entrez]
PHST- 2012/12/12 06:00 [pubmed]
PHST- 2014/02/04 06:00 [medline]
AID - 10.1002/jmri.23962 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2013 Jul;38(1):72-9. doi: 10.1002/jmri.23962. Epub 2012 Dec 
      7.