PMID- 23234354
OWN - NLM
STAT- MEDLINE
DCOM- 20131125
LR  - 20161125
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 61
IP  - 1
DP  - 2013 Jan 9
TI  - Microencapsulation of L-5-methyltetrahydrofolic acid with ascorbate improves 
      stability in baked bread products.
PG  - 247-54
LID - 10.1021/jf304229b [doi]
AB  - Fortification of foods with L-5-methyltetrahydrofolic acid (L-5-MTHF) is 
      challenging due to low stability to environmental conditions that include 
      exposure to pH, moisture, and temperature. The objective of the present study was 
      to stabilize L-5-MTHF using microencapsulation technology. L-5-MTHF microcapsules 
      constructed with different core-to-wall ratios of L-5-MTHF, both alone or in 
      combination with sodium ascorbate, yielded high (>89%) recovery of L-5-MTHF. 
      Time-of-flight secondary ion mass spectrometry (ToF-SIMS) analysis confirmed 
      successful encapsulation of L-5-MTHF with high core-to-wall ratios. 
      Microencapsulation of L-5-MTHF alone with a high core-to-wall ratio significantly 
      (p < 0.05) improved the stability of L-5-MTHF over the course of bread baking, 
      performed both in pilot plant and in commercial baking conditions. Breads made 
      with fortified flour containing sodium ascorbate coencapsulated with L-5-MTHF had 
      recoveries of L-5-MTHF that were 97% and 77%, respectively, for pilot plant and 
      bakery breads. Co-encapsulating L-5-MTHF with ascorbate also significantly (p < 
      0.05) improved stability during storage, as compared to breads that contained 
      free L-5-MTHF.
FAU - Liu, Yazheng
AU  - Liu Y
AD  - Food Nutrition and Health, University of British Columbia, Vancouver, British 
      Columbia, Canada.
FAU - Green, Timothy J
AU  - Green TJ
FAU - Wong, Philip
AU  - Wong P
FAU - Kitts, David D
AU  - Kitts DD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121221
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Tetrahydrofolates)
RN  - PQ6CK8PD0R (Ascorbic Acid)
RN  - TYK22LML8F (5-methyltetrahydrofolate)
SB  - IM
MH  - Ascorbic Acid/*chemistry
MH  - *Bread
MH  - Chromatography, High Pressure Liquid
MH  - Color
MH  - Spectrometry, Mass, Secondary Ion
MH  - Tetrahydrofolates/*chemistry
EDAT- 2012/12/14 06:00
MHDA- 2013/12/16 06:00
CRDT- 2012/12/14 06:00
PHST- 2012/12/14 06:00 [entrez]
PHST- 2012/12/14 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 10.1021/jf304229b [doi]
PST - ppublish
SO  - J Agric Food Chem. 2013 Jan 9;61(1):247-54. doi: 10.1021/jf304229b. Epub 2012 Dec 
      21.