PMID- 23236663 OWN - NLM STAT- MEDLINE DCOM- 20130118 LR - 20121214 IS - 0324-0959 (Print) IS - 0324-0959 (Linking) VI - 51 IP - 3 DP - 2012 TI - [Therapeutic outcomes in patients with cervical cancer FIGO stage IB1]. PG - 32-4 AB - OBJECTIVE: To establish overall and disease-free survival (OS and DFS) for patients with FIGO IB1 stage cervical cancer for median period of follow-up of 41 months. MATERIAL AND METHODS: Between 11.2002-11.2011 110 women with histologically confirmed cervical cancer IB1 stage were operated on by the author. Surgery was radical hysterectomy class III (Piver) and pelvic lymphonodulectomy (ovariectomy was optionally). 76 patients were submitted to adjuvant RT (TGT- 52 - 54 Gy). The period of follow-up ranges from 2 to 104 monts, median 41 monts. RESULTS: The acturial OS and DFS in patients with cervical cancer IB1 stage were estimated as 90% and 90.9%, respectively. Eleven patients had died for the period of follow-up and in 10 occurred local or distant recurrences. The time to develop recurrences was estimated as 16.81 months. Four patients developed local recurrences and six--distant metastases. CONCLUSION: Surgical and combined therapy of cervical cancer patients IB1 stage leads to high rate OS and DFS--90% and 90.9%, respectively. The incidence rate of distant metastases (5.5%)--in six patients in this stage makes pelvic lymph node dissection crucial and the presence of LM in gluteal and presacral lymph nodes requires paraaortic lymph node dissection. FAU - Kornovski, Y AU - Kornovski Y FAU - Ismail, E AU - Ismail E FAU - Kaneva, M AU - Kaneva M LA - bul PT - English Abstract PT - Journal Article PL - Bulgaria TA - Akush Ginekol (Sofiia) JT - Akusherstvo i ginekologiia JID - 0370455 SB - IM MH - Adult MH - Cervix Uteri/pathology/*radiation effects/*surgery MH - Disease-Free Survival MH - Female MH - Follow-Up Studies MH - Humans MH - Hysterectomy MH - Lymph Node Excision MH - Lymph Nodes/pathology/surgery MH - Lymphatic Metastasis/pathology/radiotherapy MH - Middle Aged MH - Neoplasm Grading MH - Pelvis/pathology/surgery MH - Radiotherapy, Adjuvant MH - Uterine Cervical Neoplasms/pathology/*radiotherapy/*surgery EDAT- 2012/12/15 06:00 MHDA- 2013/01/19 06:00 CRDT- 2012/12/15 06:00 PHST- 2012/12/15 06:00 [entrez] PHST- 2012/12/15 06:00 [pubmed] PHST- 2013/01/19 06:00 [medline] PST - ppublish SO - Akush Ginekol (Sofiia). 2012;51(3):32-4.