PMID- 23242036
OWN - NLM
STAT- MEDLINE
DCOM- 20130801
LR  - 20211021
IS  - 1432-2102 (Electronic)
IS  - 0033-832X (Linking)
VI  - 53
IP  - 1
DP  - 2013 Jan
TI  - [MRI in cardiac sarcoidosis and amyloidosis].
PG  - 54-60
LID - 10.1007/s00117-012-2386-0 [doi]
AB  - CLINICAL/METHODICAL ISSUE: Sarcoidosis and amyloidosis are both multisystem 
      disorders, which may involve the heart; however, isolated cardiac disease is 
      rare. Diagnosis of cardiac sarcoidosis and amyloidosis is crucial because the 
      patient prognosis is dependent on cardiac involvement and early treatment. 
      STANDARD RADIOLOGICAL METHODS: Echocardiography is the first line imaging 
      modality in the diagnostic work-up of both diseases, possibly giving hints 
      towards the correct diagnosis. Besides myocardial biopsy and radionuclide studies 
      cardiac magnetic resonance imaging (MRI) is routinely performed in patients 
      suspect of having infiltrative cardiomyopathy. METHODICAL INNOVATIONS: The T1 
      mapping procedure is currently being evaluated as a new technique for detection 
      and quantification of global myocardial enhancement, as seen in cardiac 
      amyloidosis. PERFORMANCE: Sensitivities and specificities for detection of 
      cardiac sarcoidosis and amyloidosis can be significantly improved by MRI, 
      especially with late gadolinium enhancement (LGE) imaging. In cardiac sarcoidosis 
      the use of LGE is outcome-related while in amyloidosis analysis of T1-mapping may 
      be of prognostic value. PRACTICAL RECOMMENDATIONS: If cardiac involvement in 
      sarcoidosis or amyloidosis is suspected cardiac MRI including LGE should be 
      performed for establishing the diagnosis.
FAU - Bauner, K U
AU  - Bauner KU
AD  - Institut fur Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universitat 
      Munchen, Campus Grosshadern, Deutschland. kerstin.bauner@med.uni-muenchen.de
FAU - Wintersperger, B
AU  - Wintersperger B
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - MRT bei kardialer Sarkoidose und Amyloidose.
PL  - Germany
TA  - Radiologe
JT  - Der Radiologe
JID - 0401257
SB  - IM
MH  - Amyloidosis/*complications/*diagnosis
MH  - Cardiomyopathies/*diagnosis/*etiology
MH  - Diagnosis, Differential
MH  - Humans
MH  - Image Enhancement/methods
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Sarcoidosis/*complications/*diagnosis
EDAT- 2012/12/18 06:00
MHDA- 2013/08/02 06:00
CRDT- 2012/12/18 06:00
PHST- 2012/12/18 06:00 [entrez]
PHST- 2012/12/18 06:00 [pubmed]
PHST- 2013/08/02 06:00 [medline]
AID - 10.1007/s00117-012-2386-0 [doi]
PST - ppublish
SO  - Radiologe. 2013 Jan;53(1):54-60. doi: 10.1007/s00117-012-2386-0.