PMID- 23247418
OWN - NLM
STAT- MEDLINE
DCOM- 20130626
LR  - 20130124
IS  - 1432-0770 (Electronic)
IS  - 0340-1200 (Linking)
VI  - 107
IP  - 1
DP  - 2013 Feb
TI  - On dependency properties of the ISIs generated by a two-compartmental neuronal 
      model.
PG  - 95-106
LID - 10.1007/s00422-012-0536-0 [doi]
AB  - One-dimensional leaky integrate and fire neuronal models describe interspike 
      intervals (ISIs) of a neuron as a renewal process and disregarding the neuron 
      geometry. Many multi-compartment models account for the geometrical features of 
      the neuron but are too complex for their mathematical tractability. Leaky 
      integrate and fire two-compartment models seem a good compromise between 
      mathematical tractability and an improved realism. They indeed allow to relax the 
      renewal hypothesis, typical of one-dimensional models, without introducing too 
      strong mathematical difficulties. Here, we pursue the analysis of the 
      two-compartment model studied by Lansky and Rodriguez (Phys D 132:267-286, 1999), 
      aiming of introducing some specific mathematical results used together with 
      simulation techniques. With the aid of these methods, we investigate dependency 
      properties of ISIs for different values of the model parameters. We show that an 
      increase of the input increases the strength of the dependence between successive 
      ISIs.
FAU - Benedetto, Elisa
AU  - Benedetto E
AD  - Department of Mathematics G. Peano, University of Torino, Via Carlo Alberto 10, 
      10123 Torino, Italy. elisa.benedetto@unito.it
FAU - Sacerdote, Laura
AU  - Sacerdote L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121218
PL  - Germany
TA  - Biol Cybern
JT  - Biological cybernetics
JID - 7502533
SB  - IM
MH  - *Models, Theoretical
MH  - Neurons/*physiology
EDAT- 2012/12/19 06:00
MHDA- 2013/06/28 06:00
CRDT- 2012/12/19 06:00
PHST- 2012/05/10 00:00 [received]
PHST- 2012/11/12 00:00 [accepted]
PHST- 2012/12/19 06:00 [entrez]
PHST- 2012/12/19 06:00 [pubmed]
PHST- 2013/06/28 06:00 [medline]
AID - 10.1007/s00422-012-0536-0 [doi]
PST - ppublish
SO  - Biol Cybern. 2013 Feb;107(1):95-106. doi: 10.1007/s00422-012-0536-0. Epub 2012 
      Dec 18.