PMID- 2324879
OWN - NLM
STAT- MEDLINE
DCOM- 19900518
LR  - 20190817
IS  - 0277-2116 (Print)
IS  - 0277-2116 (Linking)
VI  - 10
IP  - 1
DP  - 1990 Jan
TI  - Neonatal serum protein levels as indicators of nutritional status: normal values 
      and correlation with anthropometric data.
PG  - 53-61
AB  - Twenty-one infants were studied to compare cord serum protein concentrations 
      (SPCs) with samples drawn 3 days after birth. The results were compared with 
      anthropometric measurements of the infants to determine the usefulness of serum 
      studies in predicting the nutritional status of the newborn. SPCs of 19 serum 
      protein subfractions were measured by laser nephelometry. In 17 of 19 proteins, 
      the cord blood and newborn blood levels were highly correlated. C1Q and 
      haptoglobin were the exceptions. The SPC was converted to serum protein mass 
      (SPM) as follows: SPM = [(SPC) x (birth weight) x (0.85) x (1-hematocrit)]. Blood 
      volume is approximately 0.85 dl of blood/kg of body weight and since these 
      proteins are largely intravascular, it was postulated that the estimated total 
      protein mass would be a more accurate index of nutritional state. Six proteins 
      (C3, C4, prealbumin, retinol binding protein, transferrin, and albumin) were 
      highly correlated with the anthropometry (arm circumference, skin fold thickness, 
      length, weight, etc.). This study indicates that umbilical cord blood may be used 
      to estimate a newborn's nutritional status. Transport proteins such as albumin, 
      transferrin, retinol binding protein, and prealbumin are commonly used to assess 
      adult nutritional status, and may be used in infants after estimating the total 
      mass of the protein in the serum.
FAU - Raubenstine, D A
AU  - Raubenstine DA
AD  - Department of Surgery, University Hospital, College of Medicine, Pennsylvania 
      State University, Hershey 17033.
FAU - Ballantine, T V
AU  - Ballantine TV
FAU - Greecher, C P
AU  - Greecher CP
FAU - Webb, S L
AU  - Webb SL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Pediatr Gastroenterol Nutr
JT  - Journal of pediatric gastroenterology and nutrition
JID - 8211545
RN  - 0 (Blood Proteins)
SB  - IM
MH  - Anthropometry
MH  - Blood Proteins/*analysis
MH  - Body Height
MH  - Body Weight
MH  - Fetal Blood/*analysis
MH  - Gestational Age
MH  - Humans
MH  - Infant, Newborn/*physiology
MH  - Nephelometry and Turbidimetry
MH  - *Nutritional Status
MH  - Reference Values
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
AID - 10.1097/00005176-199001000-00011 [doi]
PST - ppublish
SO  - J Pediatr Gastroenterol Nutr. 1990 Jan;10(1):53-61. doi: 
      10.1097/00005176-199001000-00011.