PMID- 23251273
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211021
IS  - 1792-0981 (Print)
IS  - 1792-1015 (Electronic)
IS  - 1792-0981 (Linking)
VI  - 5
IP  - 1
DP  - 2013 Jan
TI  - Levels of B-type natriuretic peptide in chronic heart failure patients with and 
      without diabetes mellitus.
PG  - 229-232
AB  - The current study aimed to observe the value of B-type natriuretic peptide (BNP) 
      in chronic heart failure (CHF) patients with and without diabetes mellitus (DM). 
      The study consisted of 559 CHF patients, including 276 patients with coronary 
      heart disease, 234 with hypertensive heart disease and 49 with dilated 
      cardiomyopathy. The subjects were divided into non-DM and DM groups which 
      included 384 and 175 patients, respectively. Their New York Heart Association 
      (NYHA) cardiac function degree and BNP levels were detected following admission. 
      Other blood parameters, including fasting blood glucose and serum creatinine, 
      were also collected. Left ventricular ejection fraction (LVEF) and the average 
      thickness of the left ventricular wall (LVW) were detected by echocardiography. 
      The total score of the heart failure (HF)-related parameters was evaluated for 
      each patient according to age, hypertension, LVEF, LVW and NYHA degree. 
      Additionally, BNP-score relation curves were constructed. The levels of BNP were 
      significantly higher in the DM group compared with the non-DM group (1143.73+/-94.0 
      vs. 884.34+/-57.0 ng/l, P<0.05). Positive BNP-score relation curves were obtained 
      for the DM and non-DM groups, but the curve of the DM group was notably steeper. 
      As the patients with DM have significantly higher BNP levels at a similar HF 
      score, DM history and fasting blood glucose should be taken into consideration 
      when evaluating the value of BNP in HF.
FAU - Peng, Qiang
AU  - Peng Q
AD  - Department of Cardiology, Second Affiliated Hospital, Medical College of Nanchang 
      University, Nanchang, Jiangxi 330006, P.R. China.
FAU - Hu, Weitong
AU  - Hu W
FAU - Su, Hai
AU  - Su H
FAU - Yang, Qing
AU  - Yang Q
FAU - Cheng, Xiaoshu
AU  - Cheng X
LA  - eng
PT  - Journal Article
DEP - 20121023
PL  - Greece
TA  - Exp Ther Med
JT  - Experimental and therapeutic medicine
JID - 101531947
PMC - PMC3523957
EDAT- 2012/12/20 06:00
MHDA- 2012/12/20 06:01
PMCR- 2012/10/23
CRDT- 2012/12/20 06:00
PHST- 2012/07/23 00:00 [received]
PHST- 2012/10/08 00:00 [accepted]
PHST- 2012/12/20 06:00 [entrez]
PHST- 2012/12/20 06:00 [pubmed]
PHST- 2012/12/20 06:01 [medline]
PHST- 2012/10/23 00:00 [pmc-release]
AID - etm-05-01-0229 [pii]
AID - 10.3892/etm.2012.760 [doi]
PST - ppublish
SO  - Exp Ther Med. 2013 Jan;5(1):229-232. doi: 10.3892/etm.2012.760. Epub 2012 Oct 23.