PMID- 23254566
OWN - NLM
STAT- MEDLINE
DCOM- 20131118
LR  - 20211021
IS  - 1432-0703 (Electronic)
IS  - 0090-4341 (Print)
IS  - 0090-4341 (Linking)
VI  - 64
IP  - 3
DP  - 2013 Apr
TI  - Exposure assessment of organochlorine pesticides, arsenic, and lead in children 
      from the major agricultural areas in Sonora, Mexico.
PG  - 519-27
LID - 10.1007/s00244-012-9846-4 [doi]
AB  - There is a lack of information of exposure to organochlorine pesticides (OCP) and 
      some metals, such as lead (Pb) and arsenic (As), both of which were used as 
      arsenicals pesticides, in children living in the major agricultural areas of 
      Mexico. The objective of this study was to assess the exposure of children to 
      different OCP, As, and Pb in the Yaqui and Mayo valleys of Sonora to generate 
      population baseline levels of these toxins. A cross-sectional study was 
      undertaken in 165 children (age 6-12 years old) from 10 communities from both 
      valleys during 2009. Blood samples were analyzed for OCP and Pb and first morning 
      void urine for inorganic As (InAs). All of the blood samples had detectable 
      levels of dichlorodiphenyltrichloroethylene (p,p'-DDE) ranging from 0.25 to 10.3 
      mug/L. However lindane, dichlorodiphenyltrichloroethane (p,p'-DDT), aldrin, and 
      endosulfan were detected in far less of the population (36.4, 23.6, 9.1, and 3 %, 
      respectively). Methoxychlor and endrin were not found in any sample. The average 
      value of Pb in this population was 3.2 mug Pb/dL (range 0.17-9.0) with 8.5 % of 
      the samples having levels <5.0 mug Pb/dL. Urinary As levels ranged from 5.4 to 199 
      mug As/L with an average value of 31.0 mug As/L. Levels > 50 mug/L were observed in 
      12.7 % of the samples. Our results show that is important to start a 
      risk-reduction program to decrease exposure to these toxins in Mexican 
      communities. In addition, the results can be used to establish the baseline 
      levels of exposure to these toxins in this agricultural region and may be used as 
      a reference point for regulatory agencies.
FAU - Meza-Montenegro, Maria M
AU  - Meza-Montenegro MM
AD  - Department of Natural Resources, ITSON, 5 de Febrero 818 Sur, Zona Centro, 85000, 
      Cd. Obregon, Sonora, Mexico. mmeza@itson.mx
FAU - Valenzuela-Quintanar, Ana I
AU  - Valenzuela-Quintanar AI
FAU - Balderas-Cortes, Jose J
AU  - Balderas-Cortes JJ
FAU - Yanez-Estrada, Leticia
AU  - Yanez-Estrada L
FAU - Gutierrez-Coronado, Maria L
AU  - Gutierrez-Coronado ML
FAU - Cuevas-Robles, Alberto
AU  - Cuevas-Robles A
FAU - Gandolfi, A Jay
AU  - Gandolfi AJ
LA  - eng
GR  - P30 ES006694/ES/NIEHS NIH HHS/United States
GR  - P42 ES004940/ES/NIEHS NIH HHS/United States
PT  - Journal Article
DEP - 20121220
PL  - United States
TA  - Arch Environ Contam Toxicol
JT  - Archives of environmental contamination and toxicology
JID - 0357245
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 2P299V784P (Lead)
RN  - N712M78A8G (Arsenic)
SB  - IM
MH  - *Agriculture
MH  - Arsenic/*urine
MH  - Child
MH  - Cross-Sectional Studies
MH  - Environmental Exposure/*analysis
MH  - Environmental Monitoring
MH  - *Environmental Pollutants/blood/urine
MH  - Female
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*blood
MH  - Lead/*blood
MH  - Male
MH  - Mexico
MH  - Pesticides/*blood
MH  - Rural Population
PMC - PMC4023507
MID - NIHMS575147
EDAT- 2012/12/21 06:00
MHDA- 2013/11/19 06:00
PMCR- 2014/05/16
CRDT- 2012/12/21 06:00
PHST- 2012/06/18 00:00 [received]
PHST- 2012/11/05 00:00 [accepted]
PHST- 2012/12/21 06:00 [entrez]
PHST- 2012/12/21 06:00 [pubmed]
PHST- 2013/11/19 06:00 [medline]
PHST- 2014/05/16 00:00 [pmc-release]
AID - 10.1007/s00244-012-9846-4 [doi]
PST - ppublish
SO  - Arch Environ Contam Toxicol. 2013 Apr;64(3):519-27. doi: 
      10.1007/s00244-012-9846-4. Epub 2012 Dec 20.