PMID- 23256385
OWN - NLM
STAT- MEDLINE
DCOM- 20130808
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 8
DP  - 2012 Aug
TI  - [Simultaneous determination of 14 restricted substances in flavor and fragrant by 
      ultra high performance liquid chromatography].
PG  - 816-21
AB  - An ultra high performance liquid chromatographic method was established for the 
      separation and determination of 14 restricted substances in flavor and fragrant 
      samples. The sample was extracted by 10% (v/v) methanol aqueous solution 
      containing 1% (v/v) ammonia. The 14 analytes were separated in 12 min on a Waters 
      BEH C18 column (50 mm x 2.1 mm, 1.7 microm) using acetonitrile and 10 mmol/L 
      ammonium acetate aqueous solution (containing 0.1% (v/v) acetic acid) as mobile 
      phases with gradient elution at a flow rate of 0.2 mL/min and 35 degrees C, and 
      detected by a diode array detector scanned from 200 nm to 500 nm. The regression 
      equations revealed acceptable linearity (correlation coefficients ranged from 
      0.995 0 to 0.999 9) in the range of 0.10 - 50 mg/L for the 14 analytes. The 
      limits of detection (LODs) were from 0.32 mg/kg to 2.51 mg/kg. The recoveries of 
      the 14 analytes spiked in real samples at 5, 10 and 20 mg/L were 93.0% - 121% 
      with the relative standard deviations (RSDs) of 0.51% - 4.50%. With the 
      advantages of accessibility, high sensitivity and good reproducibility, this 
      simple method can be used in the simultaneous determination of the restricted 
      substances in flavor and fragrant samples.
FAU - Li, Jing
AU  - Li J
AD  - Yunnan Academy of Tobacco Science, Kunming 650106, China.
FAU - Xu, Jicang
AU  - Xu J
FAU - Li, Xuemei
AU  - Li X
FAU - Zhou, Jianguang
AU  - Zhou J
FAU - Zhu, Yan
AU  - Zhu Y
FAU - Miao, Mingming
AU  - Miao M
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Odorants/*analysis
MH  - *Taste
EDAT- 2012/12/22 06:00
MHDA- 2013/08/09 06:00
CRDT- 2012/12/22 06:00
PHST- 2012/12/22 06:00 [entrez]
PHST- 2012/12/22 06:00 [pubmed]
PHST- 2013/08/09 06:00 [medline]
AID - 10.3724/sp.j.1123.2012.03029 [doi]
PST - ppublish
SO  - Se Pu. 2012 Aug;30(8):816-21. doi: 10.3724/sp.j.1123.2012.03029.