PMID- 23263710 OWN - NLM STAT- MEDLINE DCOM- 20140715 LR - 20211021 IS - 1615-2573 (Electronic) IS - 0910-8327 (Print) IS - 0910-8327 (Linking) VI - 28 IP - 6 DP - 2013 Nov TI - Re-elevation of T-wave from day 2 to day 4 after successful percutaneous coronary intervention predicts chronic cardiac systolic dysfunction in patients with first anterior acute myocardial infarction. PG - 704-13 LID - 10.1007/s00380-012-0313-y [doi] AB - This study evaluates the clinical significance of re-elevation of T-wave in patients with ST segment elevation acute myocardial infarction (STEMI) undergoing successful percutaneous coronary intervention (PCI). Resolution of ST elevation within 24 h after reperfusion is associated with better outcome. However, little is known about the serial electrocardiography (ECG) changes and their significance. Seventy-five patients (52 men; 66 +/- 1 years) with the first anterior STEMI in whom 12-lead ECG was recorded every day from day 0 to day 8 after PCI were studied. JT interval was quartered (points 1-5), and the deviations from isoelectric line at each point were analyzed in leads V2, V3, and V4. Serial ECG showed ST resolution and T-wave inversion within 2 days after PCI in all patients at the middle of JT interval (point 3), and subsequent re-elevation of T-wave on day 4 in 73 patients (97.3 %). The patients were divided into two groups: Group A (n = 37) with less JT deviation changes (<0.25 mV) from day 2 to day 4 at point 3; and Group B (n = 38) with greater JT deviation changes (>/=0.25 mV). Group B had less retrograde collateral flow and longer JT interval in the acute phase, and lower left ventricular ejection fraction (LVEF), worse regional contractility, and higher plasma brain natriuretic peptide levels at 6 months after the onset than Group A (all P < 0.05). The JT deviation change was negatively correlated with and an independent predictor for LVEF in the chronic phase. Re-elevation >/=0.25 mV of T-wave at the middle of JT interval after successful PCI predicts chronic cardiac systolic dysfunction in patients with first anterior STEMI. FAU - Nishizaki, Fumie AU - Nishizaki F AD - Department of Cardiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan. FAU - Tomita, Hirofumi AU - Tomita H FAU - Yokoyama, Hiroaki AU - Yokoyama H FAU - Higuma, Takumi AU - Higuma T FAU - Abe, Naoki AU - Abe N FAU - Suzuki, Akiko AU - Suzuki A FAU - Endo, Tomohide AU - Endo T FAU - Tateyama, Shunta AU - Tateyama S FAU - Ishida, Yuji AU - Ishida Y FAU - Osanai, Tomohiro AU - Osanai T FAU - Okumura, Ken AU - Okumura K LA - eng PT - Journal Article DEP - 20121222 PL - Japan TA - Heart Vessels JT - Heart and vessels JID - 8511258 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Anterior Wall Myocardial Infarction/complications/diagnosis/physiopathology/*therapy MH - *Electrocardiography MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Percutaneous Coronary Intervention MH - Predictive Value of Tests MH - Retrospective Studies MH - Risk Factors MH - Stroke Volume MH - *Systole MH - Time Factors MH - Treatment Outcome MH - Ventricular Dysfunction, Left/diagnosis/*etiology/physiopathology MH - *Ventricular Function, Left PMC - PMC3830194 EDAT- 2012/12/25 06:00 MHDA- 2014/07/16 06:00 PMCR- 2012/12/22 CRDT- 2012/12/25 06:00 PHST- 2012/09/05 00:00 [received] PHST- 2012/11/30 00:00 [accepted] PHST- 2012/12/25 06:00 [entrez] PHST- 2012/12/25 06:00 [pubmed] PHST- 2014/07/16 06:00 [medline] PHST- 2012/12/22 00:00 [pmc-release] AID - 313 [pii] AID - 10.1007/s00380-012-0313-y [doi] PST - ppublish SO - Heart Vessels. 2013 Nov;28(6):704-13. doi: 10.1007/s00380-012-0313-y. Epub 2012 Dec 22.