PMID- 23271382 OWN - NLM STAT- MEDLINE DCOM- 20140422 LR - 20130822 IS - 1098-8785 (Electronic) IS - 0735-1631 (Linking) VI - 30 IP - 8 DP - 2013 Sep TI - Influence of perinatal nutrition and gestational age on neurodevelopment of very low-birth-weight preterm infants. PG - 673-80 LID - 10.1055/s-0032-1331030 [doi] AB - AIM: To assess the influence of gestational age and perinatal nutrition on development at 24 months' corrected age in a cohort of very low-birth-weight preterm infants. METHODS: One hundred twenty-five very low-birth-weight preterm infants admitted to a neonatal intensive care unit within the first 48 hours of life were studied. The infants were classified as born small for gestational age (SGA) and still SGA at discharge (SGA/SGA); born adequate for gestational age (AGA) and SGA at discharge (AGA/SGA); and born AGA and still AGA age at discharge (AGA/AGA). The Bayley Scales of Infant and Toddler Development III (BSID-III) were used for assessment of neurodevelopment at 24 months' corrected age. RESULTS: Fifty-six infants were classified as SGA/SGA, 55 as AGA/SGA, and 14 as AGA/AGA with no difference in BSID-III among the groups. By multiple linear regression analysis, the variables associated to better neurodevelopment outcome were higher gestational age and absence of grade III/IV periventricular/intraventricular hemorrhage. CONCLUSION: Immaturity is the most important variable associated with better neurodevelopment outcome in very preterm infants. CI - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. FAU - Filipouski, Gabriela R AU - Filipouski GR AD - Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul and Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil. FAU - Silveira, Rita C AU - Silveira RC FAU - Procianoy, Renato S AU - Procianoy RS LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20121227 PL - United States TA - Am J Perinatol JT - American journal of perinatology JID - 8405212 SB - IM MH - Analysis of Variance MH - Child Development/*physiology MH - Child, Preschool MH - Cohort Studies MH - Female MH - Gestational Age MH - Humans MH - Infant MH - *Infant Nutritional Physiological Phenomena MH - Infant, Newborn MH - Infant, Premature/*growth & development MH - Infant, Very Low Birth Weight/*growth & development MH - Milk, Human MH - Neuropsychological Tests MH - Parenteral Nutrition MH - Pregnancy MH - Prospective Studies MH - Regression Analysis EDAT- 2012/12/29 06:00 MHDA- 2014/04/23 06:00 CRDT- 2012/12/29 06:00 PHST- 2012/12/29 06:00 [entrez] PHST- 2012/12/29 06:00 [pubmed] PHST- 2014/04/23 06:00 [medline] AID - 10.1055/s-0032-1331030 [doi] PST - ppublish SO - Am J Perinatol. 2013 Sep;30(8):673-80. doi: 10.1055/s-0032-1331030. Epub 2012 Dec 27.