PMID- 2327408 OWN - NLM STAT- MEDLINE DCOM- 19900511 LR - 20190820 IS - 0361-8609 (Print) IS - 0361-8609 (Linking) VI - 34 IP - 1 DP - 1990 May TI - Porphyria cutanea tarda after allogeneic bone marrow transplantation for chronic myelogenous leukemia. PG - 69-70 AB - A case of porphyria cutanea tarda (PCT) occurring after bone marrow transplantation (BMT) is reported. A 43-year-old male with chronic myelogenous leukemia received an human leukocyte antigen (HLA)-identical allogeneic transplantation with T-cell depleted marrow. Because of graft rejection, a second transplant was performed 4 months later. A grade II acute graft- vs.-host disease and a cytomegalovirus (CMV) infection were subsequently observed. Two years after the second transplant, cutaneous symptoms of PCT with typical biochemical abnormalities developed. Liver biopsy revealed signs of hepatitis with iron overload. CMV was isolated from liver tissue. The possible roles of underlying disease, BMT, and CMV liver disease are discussed in view of the recently reported cases of PCT in patients with AIDS or hematological disorders. FAU - Guyotat, D AU - Guyotat D AD - Unite de Greffes de Moelle Osseuse, Hopital Edouard Herriot, Lyon, France. FAU - Nicolas, J F AU - Nicolas JF FAU - Augey, F AU - Augey F FAU - Fiere, D AU - Fiere D FAU - Thivolet, J AU - Thivolet J LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Am J Hematol JT - American journal of hematology JID - 7610369 SB - IM MH - Bone Marrow Transplantation/*adverse effects MH - Child MH - Humans MH - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*surgery MH - Male MH - Middle Aged MH - Porphyrias/*etiology MH - Skin Diseases/*etiology MH - Transplantation, Homologous/*adverse effects EDAT- 1990/05/01 00:00 MHDA- 1990/05/01 00:01 CRDT- 1990/05/01 00:00 PHST- 1990/05/01 00:00 [pubmed] PHST- 1990/05/01 00:01 [medline] PHST- 1990/05/01 00:00 [entrez] AID - 10.1002/ajh.2830340115 [doi] PST - ppublish SO - Am J Hematol. 1990 May;34(1):69-70. doi: 10.1002/ajh.2830340115.