PMID- 23275012
OWN - NLM
STAT- MEDLINE
DCOM- 20130722
LR  - 20211021
IS  - 1993-0402 (Electronic)
IS  - 1672-0415 (Linking)
VI  - 19
IP  - 1
DP  - 2013 Jan
TI  - Chinese medicine improves postoperative quality of life in endometriosis 
      patients: a randomized controlled trial.
PG  - 15-21
LID - 10.1007/s11655-012-1196-6 [doi]
AB  - OBJECTIVE: To investigate the effect of Chinese medicine (CM) and Western 
      medicine (WM) on quality of life (QOL) after conservative surgery for 
      endometriosis. METHODS: A total of 320 patients with endometriosis were 
      randomized into two groups by using random block design, CM group (160 cases, 
      activating blood circulation and removing blood stasis treatment based on 
      syndrome differentiation) and WM group (160 cases, gonadotropin-releasing hormone 
      agonist or gestrinone treatment) after conservative surgery. Treatment was given 
      for 3-6 months (according to the revised American Fertility Society scoring 
      system stage), and the World Health Organization QOL-BREF (WHOQOL-BREF) was 
      applied to patients before and after treatment to assess QOL. RESULTS: There were 
      136 cases in the CM group and 141 cases in the WM group completing therapy. In 
      the CM group, the use of the WHOQOL-BREF showed that the physical, psychological 
      and environmental scores posttreatment were significantly higher than those at 
      pre-treatment (P < 0.05), and for 12 items (pain and discomfort, energy and 
      fatigue, sleep and rest, mobility, activities of daily living, work capacity, 
      negative feelings, health and social care: accessibility and quality, 
      participation in and opportunities for recreation/leisure activities, appetite, 
      QOL score, overall health status and QOL), the difference in scores was 
      significant (P < 0.05). In the WM group, 4 items (pain and discomfort, 
      opportunities for acquiring new information and skills, QOL score, overall health 
      status and QOL) had significantly different scores post-treatment compared with 
      those at pre-treatment (P < 0.05). Before treatment, the QOL in the two groups of 
      patients showed no significant difference (P > 0.05). After treatment, the scores 
      for physical health in the CM group were significantly higher than those of the 
      WM group (P < 0.05) and the scores of 4 items (mobility, activities of daily 
      living, sexual activity, QOL score) in the CM group were significantly higher 
      than those in the WM group (P < 0.05). CONCLUSIONS: CM and WM treatment could 
      improve the QOL of patients with endometriosis after conservative surgery. CM 
      treatment is more effective than WM.
FAU - Zhao, Rui-Hua
AU  - Zhao RH
AD  - Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. 
      rhzh801@sohu.com
FAU - Liu, Yong
AU  - Liu Y
FAU - Tan, Yong
AU  - Tan Y
FAU - Hao, Zeng-Ping
AU  - Hao ZP
FAU - Meng, Qing-Wei
AU  - Meng QW
FAU - Wang, Rui
AU  - Wang R
FAU - Long, Di
AU  - Long D
FAU - Ding, Yong-Fen
AU  - Ding YF
FAU - Song, Dian-Rong
AU  - Song DR
FAU - Xu, Cai
AU  - Xu C
FAU - Ren, Zhi-Zhen
AU  - Ren ZZ
FAU - Yang, Yan-Huan
AU  - Yang YH
FAU - Wang, Ai-Ming
AU  - Wang AM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20121229
PL  - China
TA  - Chin J Integr Med
JT  - Chinese journal of integrative medicine
JID - 101181180
RN  - 0 (Drugs, Chinese Herbal)
RN  - 33515-09-2 (Gonadotropin-Releasing Hormone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - China
MH  - Drugs, Chinese Herbal/*therapeutic use
MH  - Endometriosis/diagnosis/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Gonadotropin-Releasing Hormone/*antagonists & inhibitors/therapeutic use
MH  - Humans
MH  - Middle Aged
MH  - Pain Measurement
MH  - Pain, Postoperative/*drug therapy/physiopathology
MH  - Patient Satisfaction/statistics & numerical data
MH  - Postoperative Care/methods
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Reference Values
MH  - Risk Assessment
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2013/01/01 06:00
MHDA- 2013/07/23 06:00
CRDT- 2013/01/01 06:00
PHST- 2012/05/05 00:00 [received]
PHST- 2013/01/01 06:00 [entrez]
PHST- 2013/01/01 06:00 [pubmed]
PHST- 2013/07/23 06:00 [medline]
AID - 10.1007/s11655-012-1196-6 [doi]
PST - ppublish
SO  - Chin J Integr Med. 2013 Jan;19(1):15-21. doi: 10.1007/s11655-012-1196-6. Epub 
      2012 Dec 29.