PMID- 23279734
OWN - NLM
STAT- MEDLINE
DCOM- 20140305
LR  - 20130703
IS  - 1447-0594 (Electronic)
IS  - 1447-0594 (Linking)
VI  - 13
IP  - 3
DP  - 2013 Jul
TI  - Trends in mortality rates in elderly ST elevation myocardial infarction patients 
      submitted to primary percutaneous coronary intervention: a 7-year single-center 
      experience.
PG  - 711-7
LID - 10.1111/ggi.12005 [doi]
AB  - AIM: Limited data are available on the safety and outcome of percutaneous 
      coronary intervention (PCI) in elderly patients with ST elevation myocardial 
      infarction (STEMI), as elderly patients are under-represented in randomized 
      trials. METHODS: We therefore aimed at assessing the trends in mortality rates 
      (both at short-term and at 1-year follow up) in an unselected cohort of 404 STEMI 
      patients aged >/= 75 years all submitted to primary PCI and consecutively admitted 
      to our Intensive Cardiac Care Unit from 2004 to 2010. RESULTS: In the first 
      period (2004-2006), 202 patients (202/661, 30.6%) were aged >/= 75 years, whereas 
      in the second period (2007-2010), 203 patients (203/607, 33.4%) were aged >/= 75 
      years. In the second period, STEMI patients were older (P<0.001), more diabetic 
      (P<0.001) and with a higher incidence of comorbidities (P<0.001). A significantly 
      lower use of intra-aortic balloon pump was observed, together with a reduced rate 
      of bleeding, whereas the incidence of worsening renal function significantly 
      increased (P=0.011). No difference was observed in the length of stay and in 
      mortality rate (both in-hospital and 1-year post-discharge) between the first and 
      the second period. CONCLUSIONS: According to our data, patients aged >/= 75 years 
      are characterized by an increasing number of comorbidities (in particular, a 
      higher incidence of diabetes). Over a 6-year period, despite a more advanced age, 
      early mortality (and length of stay) remained unchanged (probably thanks to a 
      significant reduction in bleeding events), and no difference was observed in 
      1-year post-discharge mortality in these patients.
CI  - (c) 2012 Japan Geriatrics Society.
FAU - Lazzeri, Chiara
AU  - Lazzeri C
AD  - Intensive Cardiac Coronary Unit, Heart and Vessel Department, Teaching Hospital 
      Careggi, Florence, Italy. lazzeric@libero.it
FAU - Valente, Serafina
AU  - Valente S
FAU - Chiostri, Marco
AU  - Chiostri M
FAU - Attana, Paola
AU  - Attana P
FAU - Picariello, Claudio
AU  - Picariello C
FAU - Gensini, Gian Franco
AU  - Gensini GF
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20121221
PL  - Japan
TA  - Geriatr Gerontol Int
JT  - Geriatrics & gerontology international
JID - 101135738
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Hospital Mortality/trends
MH  - Humans
MH  - Italy/epidemiology
MH  - Male
MH  - Myocardial Infarction/diagnosis/*mortality/surgery
MH  - *Percutaneous Coronary Intervention
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Survival Rate/trends
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - ST elevation myocardial infarction
OT  - elderly
OT  - long-term follow up
OT  - percutaneous coronary intervention
OT  - prognosis
EDAT- 2013/01/03 06:00
MHDA- 2014/03/07 06:00
CRDT- 2013/01/03 06:00
PHST- 2012/10/11 00:00 [accepted]
PHST- 2013/01/03 06:00 [entrez]
PHST- 2013/01/03 06:00 [pubmed]
PHST- 2014/03/07 06:00 [medline]
AID - 10.1111/ggi.12005 [doi]
PST - ppublish
SO  - Geriatr Gerontol Int. 2013 Jul;13(3):711-7. doi: 10.1111/ggi.12005. Epub 2012 Dec 
      21.