PMID- 23279763
OWN - NLM
STAT- MEDLINE
DCOM- 20140828
LR  - 20131122
IS  - 1743-7563 (Electronic)
IS  - 1743-7555 (Linking)
VI  - 9
IP  - 4
DP  - 2013 Dec
TI  - Multiple endocrine neoplasia type 1 (MEN1).
PG  - 297-309
LID - 10.1111/ajco.12046 [doi]
AB  - Multiple endocrine neoplasia type 1 (MEN1) is inherited in an autosomal dominant 
      fashion and predisposes to the development of hyperplastic or neoplastic changes 
      in the parathyroid and pituitary glands and the endocrine pancreas, along with 
      numerous other characteristic tumors and features. The management of each entity 
      differs to some degree from their sporadic counterparts, while the lack of a 
      genotype-phenotype correlation requires lifelong clinical, biochemical and 
      radiological screening for the development of new tumors. While the syndrome 
      itself is relatively rare (a prevalence of 1-10/100 000), it is likely that 
      health-care practitioners from numerous specialities will occasionally encounter 
      a patient with MEN1 and therefore a basic knowledge of the syndrome is important. 
      In addition, many of the associated tumors are seen commonly in sporadic form, 
      and a judicious policy is therefore required in deciding how thoroughly patients 
      who develop these tumors should be screened for MEN1. The current literature on 
      MEN1 is reviewed and key learning points are suggested for the clinician.
CI  - (c) 2012 Wiley Publishing Asia Pty Ltd.
FAU - Carroll, Richard W
AU  - Carroll RW
AD  - Endocrine, Diabetes and Research Centre, Wellington Regional Hospital, 
      Wellington, New Zealand.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20121226
PL  - Australia
TA  - Asia Pac J Clin Oncol
JT  - Asia-Pacific journal of clinical oncology
JID - 101241430
SB  - IM
MH  - Humans
MH  - Multiple Endocrine Neoplasia Type 1/*diagnosis/genetics/pathology
MH  - Pancreatic Neoplasms/*diagnosis/genetics/pathology
OTO - NOTNLM
OT  - MEN1
OT  - multiple endocrine neoplasia type 1
OT  - pancreatic neuroendocrine tumor
OT  - parathyroid
OT  - pituitary
EDAT- 2013/01/03 06:00
MHDA- 2014/08/29 06:00
CRDT- 2013/01/03 06:00
PHST- 2012/10/29 00:00 [accepted]
PHST- 2013/01/03 06:00 [entrez]
PHST- 2013/01/03 06:00 [pubmed]
PHST- 2014/08/29 06:00 [medline]
AID - 10.1111/ajco.12046 [doi]
PST - ppublish
SO  - Asia Pac J Clin Oncol. 2013 Dec;9(4):297-309. doi: 10.1111/ajco.12046. Epub 2012 
      Dec 26.